PMID- 19922253
OWN - NLM
STAT- MEDLINE
DCOM- 20100311
LR  - 20171116
IS  - 1557-7708 (Electronic)
IS  - 1075-5535 (Linking)
VI  - 15
IP  - 11
DP  - 2009 Nov
TI  - Indigenous drugs in ischemic heart disease in patients with diabetes.
PG  - 1215-21
LID - 10.1089/acm.2009.0187 [doi]
AB  - BACKGROUND: India is currently facing the silent epidemic of ischemic heart 
      disease, type 2 diabetes mellitus (T2DM), hypertension, and stroke. Both diabetes 
      and ischemic heart disease appear in Indian people a decade earlier compared to 
      whites. The recent evidence that certain medicinal plants possess hypoglycemic, 
      lipid-lowering, and immunomodulating properties on account of their rich 
      flavonoid and/or other glucose-lowering active constituents merits scientific 
      scrutiny in this regard. OBJECTIVES: The present communication aims to give a 
      brief review of those plants that could be useful in T2DM associated with 
      hypertension, ischemic heart disease, and/or dyslipidemia. METHODS: Aegle 
      marmelos (bael), Allium sativum (garlic), Curcuma domestica (turmeric), Eugenia 
      jambolana (jamun), Murraya koenigii (curry leaves), Trigonella foenum graecum 
      (fenugreek), and Terminalia arjuna (arjun) have been found to be useful in 
      diabetes associated with ischemic heart disease. Their active biomolecules have 
      been identified. They have also been demonstrated to be safe in long-term use. 
      CONCLUSIONS: Further clinical research regarding their potency and efficacy 
      vis-a-vis oral hypoglycemics needs to done.
FAU - Dwivedi, Shridhar
AU  - Dwivedi S
AD  - Department of Medicine/Preventive Cardiology, University College of Medical 
      Sciences, University of Delhi and GTB Hospital, Delhi, India.
FAU - Aggarwal, Amitesh
AU  - Aggarwal A
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Altern Complement Med
JT  - Journal of alternative and complementary medicine (New York, N.Y.)
JID - 9508124
RN  - 0 (Flavonoids)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Hypolipidemic Agents)
RN  - 0 (Immunologic Factors)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Diabetes Mellitus, Type 2/complications/*drug therapy
MH  - Dyslipidemias/complications/drug therapy
MH  - Flavonoids/pharmacology/therapeutic use
MH  - Humans
MH  - Hypertension/complications/drug therapy
MH  - Hypoglycemic Agents/pharmacology/*therapeutic use
MH  - Hypolipidemic Agents/pharmacology/*therapeutic use
MH  - Immunologic Factors/pharmacology/therapeutic use
MH  - *Magnoliopsida/chemistry
MH  - Myocardial Ischemia/etiology/*prevention & control
MH  - Plant Extracts/pharmacology/*therapeutic use
RF  - 86
EDAT- 2009/11/20 06:00
MHDA- 2010/03/12 06:00
CRDT- 2009/11/20 06:00
PHST- 2009/11/20 06:00 [entrez]
PHST- 2009/11/20 06:00 [pubmed]
PHST- 2010/03/12 06:00 [medline]
AID - 10.1089/acm.2009.0187 [doi]
PST - ppublish
SO  - J Altern Complement Med. 2009 Nov;15(11):1215-21. doi: 10.1089/acm.2009.0187.