PMID- 1992611
OWN - NLM
STAT- MEDLINE
DCOM- 19910308
LR  - 20190510
IS  - 0002-9173 (Print)
IS  - 0002-9173 (Linking)
VI  - 95
IP  - 2
DP  - 1991 Feb
TI  - Inefficacy of moving average algorithm as principal quality control procedure on 
      Technicon System H6000.
PG  - 218-21
AB  - Bull's algorithm, in its "revisited" formulation, represents one of the main 
      quality control (QC) procedures in several multichannel automatic hematological 
      analyzers. Its efficacy, however, is reduced in the theoretical event that red 
      blood cells (RBC) and hemoglobin (Hgb) undergo a concomitant analytical drift 
      while mean corpuscular volume (MCV) remains unaffected, so that a null effect is 
      registered on the related erythrocytic indices: mean corpuscular hemoglobin (MCH) 
      and mean corpuscular hemoglobin concentration (MCHC). This particular phenomenon 
      has been observed on the Technicon System H6000. Routine daily work was kept in 
      control through the use of commercial controls and fresh blood samples: a 
      reproducible positive drift of two directly measured erythrocytic parameters (RBC 
      and Hgb) and of the calculated hematocrit (Hct) was observed proportional to the 
      time of continuous use of the instrument. The usefulness of Bull's QC scheme was 
      greatly reduced: it failed to detect "out of control" situation in 38%, 15%, and 
      13% of cases in the monitoring of MCV, MCH, and MCHC, respectively, when compared 
      with the traditional 2 SD limits on QC samples.
FAU - Tramacere, P
AU  - Tramacere P
AD  - University Department of Pathology, Hospital of Desio, Milan, Italy.
FAU - Marocchi, A
AU  - Marocchi A
FAU - Gerthoux, P
AU  - Gerthoux P
FAU - Beretta, C
AU  - Beretta C
FAU - Brivio, R
AU  - Brivio R
FAU - Mocarelli, P
AU  - Mocarelli P
LA  - eng
PT  - Journal Article
PL  - England
TA  - Am J Clin Pathol
JT  - American journal of clinical pathology
JID - 0370470
SB  - IM
MH  - *Algorithms
MH  - *Autoanalysis/standards/statistics & numerical data
MH  - Blood Cell Count/*instrumentation
MH  - Erythrocyte Indices
MH  - Hematocrit/instrumentation
MH  - Hemoglobinometry/instrumentation
MH  - Humans
MH  - Leukocyte Count/*instrumentation
MH  - Quality Control
EDAT- 1991/02/01 00:00
MHDA- 1991/02/01 00:01
CRDT- 1991/02/01 00:00
PHST- 1991/02/01 00:00 [pubmed]
PHST- 1991/02/01 00:01 [medline]
PHST- 1991/02/01 00:00 [entrez]
AID - 10.1093/ajcp/95.2.218 [doi]
PST - ppublish
SO  - Am J Clin Pathol. 1991 Feb;95(2):218-21. doi: 10.1093/ajcp/95.2.218.