PMID- 19928787
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20100528
LR  - 20100223
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Linking)
VI  - 26
IP  - 5
DP  - 2010 Mar 2
TI  - Ordered nanostructured amphiphile self-assembly materials from endogenous 
      nonionic unsaturated monoethanolamide lipids in water.
PG  - 3084-94
LID - 10.1021/la903005q [doi]
AB  - The self-assembly, solid state and lyotropic liquid crystalline phase behavior of 
      a series of endogenous n-acylethanolamides (NAEs) with differing degrees of 
      unsaturation, viz., oleoyl monoethanolamide, linoleoyl monoethanolamide, and 
      linolenoyl monoethanolamide, have been examined. The studied molecules are known 
      to possess inherent biological function. Both the monoethanolamide headgroup and 
      the unsaturated hydrophobe are found to be important in dictating the 
      self-assembly behavior of these molecules. In addition, all three molecules form 
      lyotropic liquid crystalline phases in water, including the inverse bicontinuous 
      cubic diamond (Q(II)(D)) and gyroid (Q(II)(G)) phases. The ability of the NAE's 
      to form inverse cubic phases and to be dispersed into ordered nanostructured 
      colloidal particles, cubosomes, in excess water, combined with their endogenous 
      nature and natural medicinal properties, makes this new class of soft mesoporous 
      amphiphile self-assembly materials suitable candidates for investigation in a 
      variety of advanced multifunctional applications, including encapsulation and 
      controlled release of therapeutic agents and incorporation of medical imaging 
      agents.
FAU - Sagnella, Sharon M
AU  - Sagnella SM
AD  - CSIRO Molecular and Health Technologies, Bag 184, North Ryde, NSW, 1670 
      Australia.
FAU - Conn, Charlotte E
AU  - Conn CE
FAU - Krodkiewska, Irena
AU  - Krodkiewska I
FAU - Moghaddam, Minoo
AU  - Moghaddam M
FAU - Seddon, John M
AU  - Seddon JM
FAU - Drummond, Calum J
AU  - Drummond CJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
EDAT- 2009/11/26 06:00
MHDA- 2009/11/26 06:01
CRDT- 2009/11/26 06:00
PHST- 2009/11/26 06:00 [entrez]
PHST- 2009/11/26 06:00 [pubmed]
PHST- 2009/11/26 06:01 [medline]
AID - 10.1021/la903005q [doi]
PST - ppublish
SO  - Langmuir. 2010 Mar 2;26(5):3084-94. doi: 10.1021/la903005q.