PMID- 19945521
OWN - NLM
STAT- MEDLINE
DCOM- 20100820
LR  - 20211020
IS  - 1878-5891 (Electronic)
IS  - 0378-5955 (Print)
IS  - 0378-5955 (Linking)
VI  - 263
IP  - 1-2
DP  - 2010 May
TI  - Middle-ear pressure gain and cochlear partition differential pressure in 
      chinchilla.
PG  - 16-25
LID - 10.1016/j.heares.2009.11.014 [doi]
AB  - An important step to describe the effects of inner-ear impedance and pathologies 
      on middle- and inner-ear mechanics is to quantify middle- and inner-ear function 
      in the normal ear. We present middle-ear pressure gain G(MEP) and 
      trans-cochlear-partition differential sound pressure DeltaP(CP) in chinchilla 
      from 100 Hz to 30 kHz derived from measurements of intracochlear sound pressures 
      in scala vestibuli P(SV) and scala tympani P(ST) and ear-canal sound pressure 
      near the tympanic membrane P(TM). These measurements span the chinchilla's 
      auditory range. G(MEP) had constant magnitude of about 20 dB between 300 Hz and 
      20 kHz and phase that implies a 40-micros delay, values with some similarities to 
      previous measurements in chinchilla and other species. DeltaP(CP) was similar to 
      G(MEP) below about 10 kHz and lower in magnitude at higher frequencies, 
      decreasing to 0 dB at 20 kHz. The high-frequency rolloff correlates with the 
      audiogram and supports the idea that middle-ear transmission limits 
      high-frequency hearing, providing a stronger link between inner-ear 
      macromechanics and hearing. We estimate the cochlear partition impedance Z(CP) 
      from these and previous data. The chinchilla may be a useful animal model for 
      exploring the effects of non-acoustic inner-ear stimulation such as "bone 
      conduction" on cochlear mechanics.
CI  - Copyright (c) 2009 Elsevier B.V. All rights reserved.
FAU - Ravicz, Michael E
AU  - Ravicz ME
AD  - Eaton-Peabody Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear 
      Infirmary, Boston, MA 02114, USA. Mike_Ravicz@meei.harvard.edu
FAU - Slama, Michael C C
AU  - Slama MC
FAU - Rosowski, John J
AU  - Rosowski JJ
LA  - eng
GR  - R01 DC000194/DC/NIDCD NIH HHS/United States
GR  - R01 DC000194-26/DC/NIDCD NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20091127
PL  - Netherlands
TA  - Hear Res
JT  - Hearing research
JID - 7900445
SB  - IM
MH  - Acoustic Impedance Tests
MH  - Acoustic Stimulation
MH  - Animals
MH  - Biomechanical Phenomena
MH  - Chinchilla/*physiology
MH  - Cochlea/*physiology
MH  - Compliance
MH  - Ear, Middle/*physiology
MH  - Hearing/physiology
MH  - Models, Biological
MH  - Pressure
MH  - Scala Tympani/physiology
PMC - PMC2866808
MID - NIHMS161881
EDAT- 2009/12/01 06:00
MHDA- 2010/08/21 06:00
PMCR- 2011/05/01
CRDT- 2009/12/01 06:00
PHST- 2009/07/13 00:00 [received]
PHST- 2009/11/20 00:00 [revised]
PHST- 2009/11/23 00:00 [accepted]
PHST- 2009/12/01 06:00 [entrez]
PHST- 2009/12/01 06:00 [pubmed]
PHST- 2010/08/21 06:00 [medline]
PHST- 2011/05/01 00:00 [pmc-release]
AID - S0378-5955(09)00290-1 [pii]
AID - 10.1016/j.heares.2009.11.014 [doi]
PST - ppublish
SO  - Hear Res. 2010 May;263(1-2):16-25. doi: 10.1016/j.heares.2009.11.014. Epub 2009 
      Nov 27.