PMID- 19950822
OWN - NLM
STAT- MEDLINE
DCOM- 20091215
LR  - 20091202
IS  - 0172-6390 (Print)
IS  - 0172-6390 (Linking)
VI  - 56
IP  - 94-95
DP  - 2009 Sep-Oct
TI  - Clinical reappraisal of total pancreatectomy for pancreatic disease.
PG  - 1525-8
AB  - BACKGROUND/AIMS: In this study, it was reappraised the outcomes of total 
      pancreatectomy (TP), retrospectively analyzing the safety of the procedures and 
      factors associated with long-term survival. METHODOLOGY: Thirty-six consecutive 
      patients underwent TP for pancreas disease at Kobe University Hospital. The 
      outcomes of TP were evaluated, analyzing operation-related results (mortality, 
      morbidity, survival and long-term outcomes) and oncological aspects. RESULTS: 
      Postoperative morbidity was 39% (14/36) and severe complications were anastomotic 
      leakage (n=3) and liver necrosis (n=1). In benign disease, 5-year survival was 
      50%, while 5-year survival in malignant disease was 22%. Postoperative 
      glycosylated hemoglobin A1c (HbA1c) level was 7.8 +/- 1.2% at 6 months and 7.8 
      +/- 1.5% at 12 months after TP, respectively. CONCLUSION: TP is safely performed 
      and the treatment option for selectively limited pancreatic cancer and 
      intraductal papillary mucinous neoplasm of the pancreas (IPMN), when the patient 
      condition permits and offers a chance of cure, although careful long-term medical 
      care and follow-up are essential.
FAU - Fujino, Yasuhireo
AU  - Fujino Y
AD  - Department of Gastroenterological Surgery, Kobe University Graduate School of 
      Medicine, Japan. yasu120@med.kobe-u.ac.jp
FAU - Matsumoto, Ippei
AU  - Matsumoto I
FAU - Ajiki, Tetsuo
AU  - Ajiki T
FAU - Kuroda, Yoshikazu
AU  - Kuroda Y
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Hepatogastroenterology
JT  - Hepato-gastroenterology
JID - 8007849
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Morbidity
MH  - Pancreatectomy/adverse effects/*methods/mortality
MH  - Pancreatic Diseases/*surgery
EDAT- 2009/12/03 06:00
MHDA- 2009/12/16 06:00
CRDT- 2009/12/03 06:00
PHST- 2009/12/03 06:00 [entrez]
PHST- 2009/12/03 06:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
PST - ppublish
SO  - Hepatogastroenterology. 2009 Sep-Oct;56(94-95):1525-8.