PMID- 19952393 OWN - NLM STAT- MEDLINE DCOM- 20110502 LR - 20191210 IS - 1672-7347 (Print) IS - 1672-7347 (Linking) VI - 34 IP - 11 DP - 2009 Nov TI - [Methods to determine minimal clinically important difference]. PG - 1058-62 AB - There are 4 methods to determine a minimal clinically important difference (MCID) currently, namely anchor-based method, distribution-based method, opinion-based method, and literature review. The anchor-based method offers the clinical significance of MCID, but it does not consider the measurement error. The anchor-based method is limited due to difficulty to obtained a suitable anchor in most cases, and variation of MCID with the anchor. The distribution-based method takes measurement error into account, and is easily implemented. The distribution-based method can not provide the clinical explanation of MCID, and the MCID from different samples might differ from each other. There is no golden criterion to judge MCID by distribution-based method so far. The opinion-based method and literature review are based on the opinions of experts and the published literature, respectively. They are usually regarded as a supplement to anchor-based method and distribution-based method. It is suggested that anchor-based method, distribution-based method, and opinion-based method should be used together when determining a MCID. FAU - Hu, Guoqing AU - Hu G AD - Department of Epidemiology and Health Statistics, Central South University, Changsha 410078, China. huguoqing009@gmail.com FAU - Huang, Qiongfeng AU - Huang Q FAU - Huang, Zhennan AU - Huang Z FAU - Sun, Zhenqiu AU - Sun Z LA - chi PT - Journal Article PL - China TA - Zhong Nan Da Xue Xue Bao Yi Xue Ban JT - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences JID - 101230586 SB - IM MH - Activities of Daily Living MH - Clinical Medicine/*methods MH - *Health Status Indicators MH - Humans MH - Outcome Assessment, Health Care/*methods MH - *Quality of Life MH - Surveys and Questionnaires/standards MH - Treatment Outcome EDAT- 2009/12/03 06:00 MHDA- 2011/05/03 06:00 CRDT- 2009/12/03 06:00 PHST- 2009/12/03 06:00 [entrez] PHST- 2009/12/03 06:00 [pubmed] PHST- 2011/05/03 06:00 [medline] AID - 1672-7347(2009)11-1058-05 [pii] PST - ppublish SO - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Nov;34(11):1058-62.