PMID- 19961280
OWN - NLM
STAT- MEDLINE
DCOM- 20100304
LR  - 20161125
IS  - 1600-0412 (Electronic)
IS  - 0001-6349 (Linking)
VI  - 89
IP  - 2
DP  - 2010
TI  - Neutrophil gelatinase-associated lipocalin serum evaluation through normal 
      pregnancy and in pregnancies complicated by preeclampsia.
PG  - 275-8
LID - 10.3109/00016340903443676 [doi]
AB  - Neutrophil gelatinase-associated lipocalin (NGAL) was evaluated prospectively 
      through normal pregnancy and pregnancies complicated by preeclampsia syndrome. 
      Sixty women enrolled in the study were evaluated for serum NGAL levels at 9-11 
      weeks gestation, at 24-26 weeks gestation and at delivery. Thirty women were 
      affected by preeclampsia and 30 women with uncomplicated pregnancies formed the 
      control group. NGAL serum concentrations in the preeclampsia group were higher 
      compared to the control group, with significant differences in each trimester. In 
      the first trimester, the median values were: 29.9 ng/mL [interquartile range 
      (IQR) 24.1-50.1] versus 13.6 ng/mL (IQR 9.1-19.9; p < 0.001); in the second 
      trimester: 59.6 ng/mL (IQR 25.3-82.6) versus 16.3 ng/mL (IQR 11.3-23.3; p < 
      0.001); and in the third trimester: 57.2 ng/mL (IQR 18.7-70.9) versus 15.8 ng/mL 
      (IQR 9.1-22.5; p < 0.001). NGAL serum values were positively correlated with 
      systolic and diastolic blood pressure and with proteinuria.
FAU - D'Anna, Rosario
AU  - D'Anna R
AD  - Department of Obstetrics and Gynecology, University of Messina, Messina, Italy. 
      rosariodanna@tin.it
FAU - Baviera, Giovanni
AU  - Baviera G
FAU - Giordano, Domenico
AU  - Giordano D
FAU - Todarello, Giovanna
AU  - Todarello G
FAU - Russo, Silvia
AU  - Russo S
FAU - Recupero, Stefania
AU  - Recupero S
FAU - Bolignano, Davide
AU  - Bolignano D
FAU - Corrado, Francesco
AU  - Corrado F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Acta Obstet Gynecol Scand
JT  - Acta obstetricia et gynecologica Scandinavica
JID - 0370343
RN  - 0 (Acute-Phase Proteins)
RN  - 0 (LCN2 protein, human)
RN  - 0 (Lipocalin-2)
RN  - 0 (Lipocalins)
RN  - 0 (Proto-Oncogene Proteins)
SB  - IM
MH  - Acute-Phase Proteins
MH  - Blood Pressure
MH  - Case-Control Studies
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Lipocalin-2
MH  - Lipocalins/*blood
MH  - Pre-Eclampsia/*blood
MH  - Pregnancy/*blood
MH  - Pregnancy Trimesters/blood
MH  - Proteinuria/epidemiology
MH  - Proto-Oncogene Proteins/*blood
MH  - ROC Curve
MH  - Sensitivity and Specificity
EDAT- 2009/12/08 06:00
MHDA- 2010/03/05 06:00
CRDT- 2009/12/08 06:00
PHST- 2009/12/08 06:00 [entrez]
PHST- 2009/12/08 06:00 [pubmed]
PHST- 2010/03/05 06:00 [medline]
AID - 10.3109/00016340903443676 [doi]
PST - ppublish
SO  - Acta Obstet Gynecol Scand. 2010;89(2):275-8. doi: 10.3109/00016340903443676.