PMID- 19961456
OWN - NLM
STAT- MEDLINE
DCOM- 20100304
LR  - 20131121
IS  - 1747-4477 (Electronic)
IS  - 1329-1947 (Linking)
VI  - 35
IP  - 3
DP  - 2009 Dec
TI  - The relationship of pulp polyp with the presence and concentration of 
      immunoglobulin E, histamine, interleukin-4 and interleukin-12.
PG  - 164-8
LID - 10.1111/j.1747-4477.2009.00160.x [doi]
AB  - The aim of this study was to evaluate the relationship between pulp polyp 
      formation and immunoglobulin E (IgE), histamine and interleukin-4 (IL-4) as the 
      most important mediators which are involved in allergy. Thirty-two samples 
      including 16 pulp polyps and 16 normal pulps were gathered. After homogenising 
      the pulpal tissue samples, enzyme-linked immunosorbent assay (ELISA) techniques 
      were used to assess the concentration of IgE, histamine, IL-4 and IL-12. The two 
      groups showed statistically significant differences in terms of both the 
      concentration and presence of IgE, histamine and IL-4 (P < 0.001); both presence 
      and concentration of IgE, histamine and IL-4 were higher in pulp polyps than in 
      normal pulps. There is not any significant difference between case and control 
      groups regarding IL-12. The results of this study give rise to the possibility of 
      type I hypersensitivity reaction being involved in pulp polyp's pathogenesis.
FAU - Sattari, Mandana
AU  - Sattari M
AD  - Department of Immunology, Medical School, Shaheed Beheshti University of Medical 
      Sciences and Health Services, Tehran, Iran.
FAU - Haghighi, Ali K
AU  - Haghighi AK
FAU - Tamijani, Hasan D
AU  - Tamijani HD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Australia
TA  - Aust Endod J
JT  - Australian endodontic journal : the journal of the Australian Society of 
      Endodontology Inc
JID - 100888004
RN  - 187348-17-0 (Interleukin-12)
RN  - 207137-56-2 (Interleukin-4)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 820484N8I3 (Histamine)
MH  - Adolescent
MH  - Case-Control Studies
MH  - Dental Pulp/immunology
MH  - Female
MH  - Histamine/*analysis
MH  - Humans
MH  - Hyperplasia
MH  - Hypersensitivity, Immediate/immunology
MH  - Immunoglobulin E/*analysis
MH  - Interleukin-12/*analysis
MH  - Interleukin-4/*analysis
MH  - Male
MH  - Pulpitis/*immunology
EDAT- 2009/12/08 06:00
MHDA- 2010/03/05 06:00
CRDT- 2009/12/08 06:00
PHST- 2009/12/08 06:00 [entrez]
PHST- 2009/12/08 06:00 [pubmed]
PHST- 2010/03/05 06:00 [medline]
AID - AEJ160 [pii]
AID - 10.1111/j.1747-4477.2009.00160.x [doi]
PST - ppublish
SO  - Aust Endod J. 2009 Dec;35(3):164-8. doi: 10.1111/j.1747-4477.2009.00160.x.