PMID- 19963312 OWN - NLM STAT- MEDLINE DCOM- 20100504 LR - 20100201 IS - 1873-1570 (Electronic) IS - 0300-9572 (Linking) VI - 81 IP - 1 DP - 2010 Jan TI - Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma. PG - 123-5 LID - 10.1016/j.resuscitation.2009.09.032 [doi] AB - The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR. CI - Copyright 2009 Elsevier Ireland Ltd. All rights reserved. FAU - Elbers, Paul W G AU - Elbers PW AD - Department of Anesthesia, Intensive Care and Pain Management, St. Antonius Ziekenhuis, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands. info@acidbase.org FAU - Craenen, Antonius J AU - Craenen AJ FAU - Driessen, Antoine AU - Driessen A FAU - Stehouwer, Marco C AU - Stehouwer MC FAU - Munsterman, Luuk AU - Munsterman L FAU - Prins, Miranda AU - Prins M FAU - van Iterson, Mat AU - van Iterson M FAU - Bruins, Peter AU - Bruins P FAU - Ince, Can AU - Ince C LA - eng PT - Case Reports PT - Journal Article DEP - 20091205 PL - Ireland TA - Resuscitation JT - Resuscitation JID - 0332173 SB - IM CIN - Resuscitation. 2010 Jan;81(1):5. PMID: 20004508 MH - Adult MH - *Cardiopulmonary Resuscitation MH - Fatal Outcome MH - Humans MH - Hypothermia/physiopathology/*therapy MH - Male MH - *Microcirculation MH - *Microscopy, Polarization MH - Near Drowning/physiopathology/*therapy MH - Rewarming/*methods EDAT- 2009/12/08 06:00 MHDA- 2010/05/05 06:00 CRDT- 2009/12/08 06:00 PHST- 2009/08/13 00:00 [received] PHST- 2009/09/05 00:00 [revised] PHST- 2009/09/26 00:00 [accepted] PHST- 2009/12/08 06:00 [entrez] PHST- 2009/12/08 06:00 [pubmed] PHST- 2010/05/05 06:00 [medline] AID - S0300-9572(09)00549-8 [pii] AID - 10.1016/j.resuscitation.2009.09.032 [doi] PST - ppublish SO - Resuscitation. 2010 Jan;81(1):123-5. doi: 10.1016/j.resuscitation.2009.09.032. Epub 2009 Dec 5.