PMID- 19964886
OWN - NLM
STAT- MEDLINE
DCOM- 20100402
LR  - 20200928
IS  - 2375-7477 (Print)
IS  - 2375-7477 (Linking)
VI  - 2009
DP  - 2009
TI  - In vitro adhesion measurements between skin and micropatterned 
      poly(dimethylsiloxane) surfaces.
PG  - 6018-21
LID - 10.1109/IEMBS.2009.5334532 [doi]
AB  - Micropatterned adhesive surfaces may have potential in reconstructive surgery. 
      The adhesion performance of mice ear skin to micropatterned 
      poly(dimethylsiloxane) (PDMS) was investigated, under in vitro conditions, and 
      compared to flat substrates. No significant difference in separation force F was 
      observed between flat substrates and micropatterned surfaces with pillar arrays. 
      However, the energy necessary for separation of the substrate from the skin was 
      sensitive to the topography. Furthermore, our results show that the 
      force-displacement curves depended on the wetness of the skin: Highest force 
      values were obtained for fresh skin while the forces decreased as the skin dried 
      out. The results are encouraging for further studies on the potential of 
      patterned PDMS in biomedical applications.
FAU - De Souza, E J
AU  - De Souza EJ
AD  - INM, Leibniz-Institut fur Neue Materialien gGmbH, Campus D2, 2D-66123 
      Saarbrucken, Germany. emersonjose.desouza@inm-gmbh.de
FAU - Kamperman, M
AU  - Kamperman M
FAU - Castellanos, G
AU  - Castellanos G
FAU - Kroner, E
AU  - Kroner E
FAU - Armbruester, V
AU  - Armbruester V
FAU - Romann, M S
AU  - Romann MS
FAU - Schick, B
AU  - Schick B
FAU - Arzt, E
AU  - Arzt E
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Annu Int Conf IEEE Eng Med Biol Soc
JT  - Annual International Conference of the IEEE Engineering in Medicine and Biology 
      Society. IEEE Engineering in Medicine and Biology Society. Annual International 
      Conference
JID - 101763872
RN  - 0 (Biocompatible Materials)
RN  - 0 (Dimethylpolysiloxanes)
RN  - 0 (Nylons)
RN  - 0 (poly(dimethylsiloxane)-polyamide copolymer)
SB  - IM
MH  - Adhesiveness
MH  - Animals
MH  - Biocompatible Materials/*chemistry
MH  - Dimethylpolysiloxanes/*chemistry
MH  - Equipment Failure Analysis
MH  - Materials Testing
MH  - Mice
MH  - Nylons/*chemistry
MH  - Prosthesis Design
MH  - *Skin Physiological Phenomena
MH  - *Skin, Artificial
MH  - Surface Properties
EDAT- 2009/12/08 06:00
MHDA- 2010/04/03 06:00
CRDT- 2009/12/08 06:00
PHST- 2009/12/08 06:00 [entrez]
PHST- 2009/12/08 06:00 [pubmed]
PHST- 2010/04/03 06:00 [medline]
AID - 10.1109/IEMBS.2009.5334532 [doi]
PST - ppublish
SO  - Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6018-21. doi: 
      10.1109/IEMBS.2009.5334532.