PMID- 19967475
OWN - NLM
STAT- MEDLINE
DCOM- 20100820
LR  - 20211020
IS  - 1532-2807 (Electronic)
IS  - 1219-4956 (Linking)
VI  - 16
IP  - 2
DP  - 2010 Jun
TI  - Extraosseus plasmacytoma of the pharynx with localized light chain deposition. 
      Case report.
PG  - 249-52
LID - 10.1007/s12253-009-9218-1 [doi]
AB  - Light chain deposition disease (LCDD) is a rare disorder associated with a clonal 
      proliferation of plasma cells, which synthesize abnormal monoclonal 
      immunoglobulin light chains. It is characterized by systemic deposition of light 
      chains in various organs, with the kidneys being most commonly affected. There 
      have been few reports of isolated LCDD, i.e. in the brain, lungs and cervical 
      lymph nodes. We here report on another patient with an isolated form of LCDD, 
      which was limited to the pharyngeal mucosa and was associated with an extraosseus 
      plasmacytoma of the pharynx, expanding the spectrum that has been recognized for 
      LCDD. The patient was treated by local radiotherapy, with an excellent response. 
      A less aggressive clinical course can probably be expected than in the usual form 
      of LCDD, but a long-term follow-up is necessary to establish the clinical 
      significance of this variant of LCDD.
FAU - Zidar, Nina
AU  - Zidar N
AD  - Institute of Pathology, Faculty of Medicine, University of Ljubljana, Korytkova 
      2, 1000, Ljubljana, Slovenia. nina.zidar@mf.uni-lj.si
FAU - Zver, Samo
AU  - Zver S
FAU - Jurcic, Vesna
AU  - Jurcic V
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20091205
PL  - Switzerland
TA  - Pathol Oncol Res
JT  - Pathology oncology research : POR
JID - 9706087
RN  - 0 (Immunoglobulin Light Chains)
SB  - IM
MH  - Humans
MH  - *Immunoglobulin Light Chains
MH  - Male
MH  - Microscopy, Electron, Transmission
MH  - Middle Aged
MH  - Paraproteinemias/complications/*pathology/radiotherapy
MH  - Pharyngeal Neoplasms/complications/*pathology/radiotherapy
MH  - Plasmacytoma/complications/*pathology/radiotherapy
EDAT- 2009/12/08 06:00
MHDA- 2010/08/21 06:00
CRDT- 2009/12/08 06:00
PHST- 2009/08/04 00:00 [received]
PHST- 2009/10/20 00:00 [accepted]
PHST- 2009/12/08 06:00 [entrez]
PHST- 2009/12/08 06:00 [pubmed]
PHST- 2010/08/21 06:00 [medline]
AID - 10.1007/s12253-009-9218-1 [doi]
PST - ppublish
SO  - Pathol Oncol Res. 2010 Jun;16(2):249-52. doi: 10.1007/s12253-009-9218-1. Epub 
      2009 Dec 5.