PMID- 19996469
OWN - NLM
STAT- MEDLINE
DCOM- 20100204
LR  - 20101118
IS  - 0023-7213 (Print)
IS  - 0023-7213 (Linking)
VI  - 95
IP  - 12
DP  - 2009 Dec
TI  - [Results of pneumonectomy for non-small cell lung cancer in Iceland].
PG  - 823-9
AB  - OBJECTIVE: Study the indications, complications and surgical outcome of 
      pneumonectomy for non small cell lung cancer (NSCLC) in Iceland MATERIAL AND 
      METHODS: A retrospective study of all pneumonectomies performed for NSCLC in 
      Iceland from 1988 to 2007. Information was obtained from medical records and data 
      on operative indications, postoperative TNM stage, complications, survival and 
      survival predictors was analysed. RESULTS: 77 patients (64% males) with mean age 
      of 62.3 yrs. were operated on, 44% on the right side. Mediastinoscopy was 
      performed in 31% of cases. Most patients were stage I or II (58%), but 17 and 21% 
      were stage III A and IIIB, respectively. Mean operation time was 161 min., 
      bleeding 1.1 L and hospital stay 11 days. Atrial fibrillation (21%), pneumonia 
      (6.5%), empyema (5.5%) and respiratory failure (5%) were the most common 
      complications. Three (3.9%) patients died within 30 days from surgery. Five year 
      survival was 20.7%. Age, history of COPD, adenocarcinoma histology and advanced 
      TNM stage were independent predictors of poor survival. CONCLUSIONS: 
      Pneumonectomies for NSCLC in Iceland have a low rate of complications and 
      operative mortality. However, long term survival is lower than expected, and many 
      patients (27%) were in advanced stages. This is most likely due to inadequate 
      preoperative staging.
FAU - Thorsteinsson, Hunbogi
AU  - Thorsteinsson H
AD  - Laeknadeild HI, Landspitals Hringbraut, Reykjavik.
FAU - Jonsson, Steinn
AU  - Jonsson S
FAU - Alfredsson, Hordur
AU  - Alfredsson H
FAU - Isaksson, Helgi J
AU  - Isaksson HJ
FAU - Gudbjartsson, Tomas
AU  - Gudbjartsson T
LA  - ice
PT  - English Abstract
PT  - Journal Article
TT  - Arangur lungnabrottnamsadgerda vid lungnakrabbameini a Islandi.
PL  - Iceland
TA  - Laeknabladid
JT  - Laeknabladid
JID - 7901326
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Non-Small-Cell Lung/mortality/pathology/*surgery
MH  - Female
MH  - Humans
MH  - Iceland/epidemiology
MH  - Kaplan-Meier Estimate
MH  - Lung Neoplasms/mortality/pathology/*surgery
MH  - Male
MH  - Mediastinoscopy
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - *Pneumonectomy/adverse effects/mortality
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2009/12/10 06:00
MHDA- 2010/02/05 06:00
CRDT- 2009/12/10 06:00
PHST- 2009/12/10 06:00 [entrez]
PHST- 2009/12/10 06:00 [pubmed]
PHST- 2010/02/05 06:00 [medline]
PST - ppublish
SO  - Laeknabladid. 2009 Dec;95(12):823-9.