PMID- 20000039
OWN - NLM
STAT- MEDLINE
DCOM- 20100603
LR  - 20091216
IS  - 1004-5619 (Print)
IS  - 1004-5619 (Linking)
VI  - 25
IP  - 5
DP  - 2009 Oct
TI  - [Expression of monocyte chemoattractant protein-1 in sudden death due to viral 
      myocarditis and its medicolegal significance].
PG  - 334-6
AB  - OBJECTIVE: To explore the expression and significance of monocyte chemoattractant 
      protein-1 (MCP-1) in myocardium in sudden death caused by viral myocarditis 
      (VMC). METHODS: To investigate the expression of MCP-1 in VMC sudden death group 
      and control group using improved immunohistochemical technique and to compare the 
      difference of the expression of MCP-1 between two groups with statistical method. 
      RESULTS: In VMC sudden death group, MCP-1 was positively expressed in 17 of 20 
      cases. While only 4 of the 20 cases in the control group showed a mildly positive 
      expression sparsely in myocardium, and the rest cases were completely negative. 
      The rate of positive expression of MCP-1 in VMC group was obviously higher than 
      that of the control group (P<0.01). CONCLUSION: The expression of MCP-1 detected 
      by immunohistochemistry provides an objective morphologic evidence for the 
      diagnosis of VMC sudden death in forensic pathology.
FAU - Ning, Juan
AU  - Ning J
AD  - Department of Forensic Pathology, Wannan Medical College, Wuhu, China. 
      ningjuan67826@126.com
FAU - Li, Yong-Hong
AU  - Li YH
FAU - Zhang, Chun-Bing
AU  - Zhang CB
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Fa Yi Xue Za Zhi
JT  - Fa yi xue za zhi
JID - 9426151
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Autopsy
MH  - Case-Control Studies
MH  - Chemokine CCL2/*metabolism
MH  - Child
MH  - Child, Preschool
MH  - *Death, Sudden, Cardiac
MH  - Female
MH  - Forensic Pathology
MH  - Humans
MH  - Immunohistochemistry
MH  - Male
MH  - Middle Aged
MH  - Myocarditis/*metabolism/pathology/virology
MH  - Myocardium/*metabolism/pathology
MH  - Staining and Labeling
MH  - Young Adult
EDAT- 2009/12/17 06:00
MHDA- 2010/06/04 06:00
CRDT- 2009/12/17 06:00
PHST- 2009/12/17 06:00 [entrez]
PHST- 2009/12/17 06:00 [pubmed]
PHST- 2010/06/04 06:00 [medline]
PST - ppublish
SO  - Fa Yi Xue Za Zhi. 2009 Oct;25(5):334-6.