PMID- 20009922
OWN - NLM
STAT- MEDLINE
DCOM- 20100429
LR  - 20101118
IS  - 1473-5830 (Electronic)
IS  - 0954-6928 (Linking)
VI  - 21
IP  - 2
DP  - 2010 Mar
TI  - Comparison of outcomes in young versus nonyoung patients with ST elevation 
      myocardial infarction treated by primary angioplasty.
PG  - 72-7
LID - 10.1097/MCA.0b013e328334a0f6 [doi]
AB  - OBJECTIVES: We sought to determine in-hospital and intermediate-term outcomes of 
      primary percutaneous coronary intervention (PCI) for ST elevation myocardial 
      infarction (STEMI) in young adults. METHODS: We reviewed 2424 consecutive 
      patients treated with primary angioplasty for acute MI; 465 were aged 45 or less 
      (young group) and 1959 were 46-74 years of age (nonyoung group). Clinical 
      characteristics, in-hospital and intermediate-term outcomes of primary PCI were 
      analyzed. RESULTS: Compared with nonyoung patients, the young patients had 
      significantly lower in-hospital and intermediate-term mortality (for in-hospital 
      mortaliy: 5.4 vs. 1.2%, P<0.001; for intermediate-term mortality: 5 vs. 1.3%, 
      P<0.001). By multivariate Cox regression analysis in all 2424 patients; 
      cardiogenic shock, diabetes mellitus, anterior MI and unsuccessful procedure were 
      independent predictors of both in-hospital and intermediate-term mortality 
      whereas age [odds ratio (OR): 1.07, P<0.001], female sex (OR: 1.88, P = 0.04), MI 
      history (OR: 3.05, P = 0.001) and multivessel disease (OR: 2.15, P = 0.01) were 
      independent predictors of only intermediate-term mortality. The young group had 
      lower unsuccessful procedure rates of primary PCI for STEMI (4.9 vs. 10.1%, P = 
      0.001). CONCLUSION: These results suggest that young adults who underwent primary 
      PCI have favorable in-hospital and intermediate-term outcomes. Moreover, primary 
      PCI for young adults with STEMI is safer, more feasible and effective than for a 
      relatively older population.
FAU - Ergelen, Mehmet
AU  - Ergelen M
AD  - Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery 
      Center, Training and Research Hospital, Istanbul 34750, Turkey. 
      drmerg@hotmail.com
FAU - Uyarel, Huseyin
AU  - Uyarel H
FAU - Gorgulu, Sevket
AU  - Gorgulu S
FAU - Norgaz, Tugrul
AU  - Norgaz T
FAU - Ayhan, Erkan
AU  - Ayhan E
FAU - Akkaya, Emre
AU  - Akkaya E
FAU - Cicek, Gokhan
AU  - Cicek G
FAU - Isik, Turgay
AU  - Isik T
FAU - Gunaydin, Zeki Yuksel
AU  - Gunaydin ZY
FAU - Soylu, Ozer
AU  - Soylu O
FAU - Ugur, Murat
AU  - Ugur M
FAU - Yildirim, Aydin
AU  - Yildirim A
FAU - Tezel, Tuna
AU  - Tezel T
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Coron Artery Dis
JT  - Coronary artery disease
JID - 9011445
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - *Angioplasty, Balloon, Coronary/adverse effects/mortality
MH  - Chi-Square Distribution
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/mortality/*therapy
MH  - Odds Ratio
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2009/12/17 06:00
MHDA- 2010/04/30 06:00
CRDT- 2009/12/17 06:00
PHST- 2009/12/17 06:00 [entrez]
PHST- 2009/12/17 06:00 [pubmed]
PHST- 2010/04/30 06:00 [medline]
AID - 10.1097/MCA.0b013e328334a0f6 [doi]
PST - ppublish
SO  - Coron Artery Dis. 2010 Mar;21(2):72-7. doi: 10.1097/MCA.0b013e328334a0f6.