PMID- 20011617
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240312
IS  - 1521-3927 (Electronic)
IS  - 1022-1336 (Print)
IS  - 1022-1336 (Linking)
VI  - 30
IP  - 16
DP  - 2009 Jun 22
TI  - Rapid Formation of Acrylated Microstructures by Microwave-Induced Thermal 
      Crosslinking.
PG  - 1382-1386
AB  - We present a rapid and highly efficient method to form microstructure of 
      poly(ethylene glycol) (PEG)-based acrylates by microwave-induced thermal 
      crosslinking. PEG-based polymeric microstructures such as polymer microarrays and 
      microwells were fabricated on 3-(trimethoxysilyl)propyl methacrylate 
      (TMSPMA)-coated glass slides that were placed on top of a silicon wafer. In 
      comparison to ultraviolet (UV) irradiation curing, microwave-induced thermal 
      crosslinking could be completed within 10 s, without thermal degradation or 
      oxygen inhibition in the presence of ambient oxygen. Furthermore, the activation 
      of surviving free radical impurities by microwave-induced heating enabled 
      crosslinking even without an exogenous radical initiator (e.g., 
      2,2'-azoisobutyronitrile (AIBN)). This approach can be beneficial for fabricating 
      various PEG-based microstructures for high-throughput screening assays, 
      cell-based biosensors, and biomedical microdevices.
FAU - Lee, Seung Hwan
AU  - Lee SH
AD  - Center for Biomedical Engineering, Department of Medicine, Brigham and Women's 
      Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
FAU - Lee, Won Gu
AU  - Lee WG
FAU - Chung, Bong Geun
AU  - Chung BG
FAU - Park, Jae Hong
AU  - Park JH
FAU - Khademhosseini, Ali
AU  - Khademhosseini A
LA  - eng
GR  - R21 EB009196/EB/NIBIB NIH HHS/United States
GR  - R21 EB009196-01/EB/NIBIB NIH HHS/United States
GR  - RL1 DE019024/DE/NIDCR NIH HHS/United States
GR  - R21 EB007249/EB/NIBIB NIH HHS/United States
GR  - R01 HL092836/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PL  - Germany
TA  - Macromol Rapid Commun
JT  - Macromolecular rapid communications
JID - 9888239
PMC - PMC2790285
MID - NIHMS160568
EDAT- 2009/12/17 06:00
MHDA- 2009/12/17 06:01
PMCR- 2009/12/08
CRDT- 2009/12/17 06:00
PHST- 2009/12/17 06:00 [entrez]
PHST- 2009/12/17 06:00 [pubmed]
PHST- 2009/12/17 06:01 [medline]
PHST- 2009/12/08 00:00 [pmc-release]
AID - 10.1002/marc.200900199 [doi]
PST - ppublish
SO  - Macromol Rapid Commun. 2009 Jun 22;30(16):1382-1386. doi: 10.1002/marc.200900199.