PMID- 20031432
OWN - NLM
STAT- MEDLINE
DCOM- 20100618
LR  - 20100312
IS  - 1872-9800 (Electronic)
IS  - 0969-8043 (Linking)
VI  - 68
IP  - 4-5
DP  - 2010 Apr-May
TI  - New type of cells with multiple chromosome rearrangements.
PG  - 844-7
LID - 10.1016/j.apradiso.2009.11.075 [doi]
AB  - A comparative analysis of the distribution and the frequency of multiaberrant 
      cells (MAC) among lymphocytes in different categories of low dose (up to 0.5 Gy) 
      irradiated people was carried out. The highest MAC frequency was observed in 
      people exposed to alpha-radiation (Pu, Rn) and in cosmonauts. This fact allows 
      MAC to be considered as an indicator of a high-energy local exposure. A new type 
      of cells with multiple chromosome rearrangements was discovered in the course of 
      analysis of stable aberrations by the fluorescence in situ hybridization (FISH) 
      method. The biological consequences of MAC formation and possibility of revealing 
      the whole diversity of cells with multiple aberrations by means of modern 
      molecular-cytogenetic methods are discussed.
CI  - Copyright 2009 Elsevier Ltd. All rights reserved.
FAU - Aseeva, Elena A
AU  - Aseeva EA
AD  - National Research Centre for Hematology, Russian Academy of Medical Sciences, 
      Moscow, Russia.
FAU - Snigiryova, Galina P
AU  - Snigiryova GP
FAU - Neverova, Anna L
AU  - Neverova AL
FAU - Bogomazova, Alexandra N
AU  - Bogomazova AN
FAU - Novitskaya, Natalia N
AU  - Novitskaya NN
FAU - Khazins, Eva D
AU  - Khazins ED
FAU - Domracheva, Elena V
AU  - Domracheva EV
LA  - eng
PT  - Journal Article
DEP - 20091205
PL  - England
TA  - Appl Radiat Isot
JT  - Applied radiation and isotopes : including data, instrumentation and methods for 
      use in agriculture, industry and medicine
JID - 9306253
SB  - IM
MH  - Alpha Particles
MH  - Cells, Cultured
MH  - Chromosome Aberrations/*radiation effects
MH  - Cytogenetic Analysis/*methods
MH  - Dose-Response Relationship, Radiation
MH  - Female
MH  - Humans
MH  - Lymphocytes/*classification/*physiology/radiation effects
MH  - Male
MH  - Radiation Dosage
MH  - Species Specificity
EDAT- 2009/12/25 06:00
MHDA- 2010/06/19 06:00
CRDT- 2009/12/25 06:00
PHST- 2009/12/25 06:00 [entrez]
PHST- 2009/12/25 06:00 [pubmed]
PHST- 2010/06/19 06:00 [medline]
AID - S0969-8043(09)00764-7 [pii]
AID - 10.1016/j.apradiso.2009.11.075 [doi]
PST - ppublish
SO  - Appl Radiat Isot. 2010 Apr-May;68(4-5):844-7. doi: 
      10.1016/j.apradiso.2009.11.075. Epub 2009 Dec 5.