PMID- 20034233 OWN - NLM STAT- MEDLINE DCOM- 20100128 LR - 20191111 IS - 0304-4920 (Print) IS - 0304-4920 (Linking) VI - 52 IP - 5 DP - 2009 Oct 31 TI - Serum heat shock protein after simulated deep diving in Navy divers. PG - 295-8 AB - Deep sea diving might cause a tremendous physical or psychological stress to the divers. The present study aims to evaluate the stress response to a simulated wet dive in Navy divers. Nineteen Navy divers took part in this study when they were undergoing annual deep dive training. Ten divers were exposed to 190 feet of sea water (fsw) breathing compressed air on day 1 and to 250 fsw breathing helium-oxygen (Heliox) gas mixture on day 3. Another 9 divers were exposed to 220 fsw on day 1 and 285 fsw on day 3 breathing Heliox gas mixture. The bottom time ranged from 5 to 8 min, and then the standard U.S. Navy air and Heliox decompression tables were followed for surfacing. Predive levels of serum heat shock protein 72 (sHsp72) were 9.95 +/- 0.56 ng/ml, which were significantly higher than those in the control group (8.01 +/- 0.77 ng/ml). After simulating Heliox dive, the sHsp72 increased to 10.43 +/- 0.56 ng/ml, but this was not statistically significant. Our results demonstrated that the serum level of Hsp72 is higher in the Navy divers who underwent regular intensive exercise. However, it remains unknown whether this increase of stress protein is associated with the diving stress or exercise preconditioning in the Navy divers. FAU - Lee, Hui-Chieh AU - Lee HC AD - Diving Medicine, Zuo-Ying Armed Forces General Hospital, Kaohsiung, ROC. FAU - Chen, Yin-Shin AU - Chen YS FAU - Kang, Bor-Hwang AU - Kang BH FAU - Wan, Fan-Jong AU - Wan FJ FAU - Chang, Lu-Peng AU - Chang LP FAU - Huang, Kun-Lun AU - Huang KL LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - India TA - Chin J Physiol JT - The Chinese journal of physiology JID - 7804502 RN - 0 (HSP72 Heat-Shock Proteins) RN - 206GF3GB41 (Helium) RN - 58933-55-4 (heliox) RN - S88TT14065 (Oxygen) SB - IM EIN - Chin J Physiol. 2009 Dec 31;52(6):455 MH - Administration, Inhalation MH - Adult MH - Decompression MH - Diving/*physiology MH - Exercise/*physiology MH - HSP72 Heat-Shock Proteins/*blood MH - Helium/administration & dosage MH - Humans MH - Oxygen/administration & dosage MH - Stress, Physiological/physiology EDAT- 2009/12/26 06:00 MHDA- 2010/01/29 06:00 CRDT- 2009/12/26 06:00 PHST- 2009/12/26 06:00 [entrez] PHST- 2009/12/26 06:00 [pubmed] PHST- 2010/01/29 06:00 [medline] AID - 10.4077/cjp.2009.amh042 [doi] PST - ppublish SO - Chin J Physiol. 2009 Oct 31;52(5):295-8. doi: 10.4077/cjp.2009.amh042.