PMID- 20041004 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20211020 IS - 1687-9759 (Electronic) IS - 1687-9740 (Print) IS - 1687-9740 (Linking) VI - 2009 DP - 2009 TI - Progressive Multifocal Leukoencephalopathy in HIV-Infected Children: A Case Report and Literature Review. PG - 348507 LID - 10.1155/2009/348507 [doi] LID - 348507 AB - We report a case of a perinatally HIV-infected patient aged 9 years, who presented with right-sided hemiplegia. His initial CD4 T-cell was of 0.21% (4 cells/muL) and plasma HIV RNA virus of 185 976 copies/mL (log 5.27). Plasma and CSF samples were subsequently positive for JCV. Twelve days after the initiation of highly active antiretroviral therapy (HAART), the MRI showed progressive white matter lesions with asymmetrical deep and subcortical white matter lesions over the left frontotemporoparietal region and the right frontal lobe. Immune Reconstitution Inflammatory Syndrome (IRIS) was suspected, and the patient was treated with methylprednisolone. His clinical symptoms worsened and despite therapy the patient deteriorated. FAU - Oberdorfer, Peninnah AU - Oberdorfer P AD - Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. FAU - Washington, Charles H AU - Washington CH FAU - Katanyuwong, Kamornwan AU - Katanyuwong K FAU - Jittamala, Podjanee AU - Jittamala P LA - eng PT - Case Reports DEP - 20090916 PL - Egypt TA - Int J Pediatr JT - International journal of pediatrics JID - 101517077 PMC - PMC2778135 EDAT- 2009/12/31 06:00 MHDA- 2009/12/31 06:01 PMCR- 2009/09/16 CRDT- 2009/12/31 06:00 PHST- 2009/02/02 00:00 [received] PHST- 2009/06/13 00:00 [accepted] PHST- 2009/12/31 06:00 [entrez] PHST- 2009/12/31 06:00 [pubmed] PHST- 2009/12/31 06:01 [medline] PHST- 2009/09/16 00:00 [pmc-release] AID - 10.1155/2009/348507 [doi] PST - ppublish SO - Int J Pediatr. 2009;2009:348507. doi: 10.1155/2009/348507. Epub 2009 Sep 16.