PMID- 20043344 OWN - NLM STAT- MEDLINE DCOM- 20100722 LR - 20211020 IS - 1932-8737 (Electronic) IS - 0160-9289 (Print) IS - 0160-9289 (Linking) VI - 33 IP - 2 DP - 2010 Feb TI - Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in congestive heart failure patients. PG - E27-30 LID - 10.1002/clc.20602 [doi] AB - BACKGROUND: Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. HYPOTHESIS: To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. METHODS: A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography. RESULTS: A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = - 0.619; P = .003, respectively). CONCLUSIONS: Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges. CI - Copyright 2010 Wiley Periodicals, Inc. FAU - Tomaello, Luca AU - Tomaello L AD - Department of Biomedical and Surgical Sciences, University of Verona, Italy. luca.tomaello@libero.it FAU - Zanolla, Luisa AU - Zanolla L FAU - Vassanelli, Corrado AU - Vassanelli C FAU - LoCascio, Vincenzo AU - LoCascio V FAU - Ferrari, Marcello AU - Ferrari M LA - eng PT - Journal Article PL - United States TA - Clin Cardiol JT - Clinical cardiology JID - 7903272 SB - IM MH - Aged MH - Arrhythmias, Cardiac/diagnosis/etiology/*prevention & control MH - *Defibrillators, Implantable MH - Echocardiography MH - Electric Countershock/*instrumentation MH - Heart Failure/complications/diagnosis/epidemiology/*therapy MH - Humans MH - Hypoxia/etiology MH - Male MH - Middle Aged MH - Polysomnography MH - Prevalence MH - *Primary Prevention MH - Retrospective Studies MH - Severity of Illness Index MH - Sleep Apnea Syndromes/diagnosis/epidemiology/*etiology MH - Treatment Outcome MH - Ventricular Dysfunction, Left/etiology PMC - PMC6653285 EDAT- 2010/01/01 06:00 MHDA- 2010/07/23 06:00 PMCR- 2009/12/30 CRDT- 2010/01/01 06:00 PHST- 2010/01/01 06:00 [entrez] PHST- 2010/01/01 06:00 [pubmed] PHST- 2010/07/23 06:00 [medline] PHST- 2009/12/30 00:00 [pmc-release] AID - CLC20602 [pii] AID - 10.1002/clc.20602 [doi] PST - ppublish SO - Clin Cardiol. 2010 Feb;33(2):E27-30. doi: 10.1002/clc.20602.