PMID- 20046634
OWN - NLM
STAT- MEDLINE
DCOM- 20100311
LR  - 20211020
IS  - 1928-9022 (Electronic)
IS  - 0830-9000 (Print)
IS  - 0830-9000 (Linking)
VI  - 73
IP  - 4
DP  - 2009 Oct
TI  - Prevalence of infection with porcine circovirus-2 (PCV-2) and porcine 
      reproductive and respiratory syndrome virus (PRRSV) in an integrated swine 
      production system experiencing postweaning multisystemic wasting syndrome.
PG  - 308-12
AB  - The objective of this study was to evaluate the prevalence of infection with 
      porcine circovirus-2 (PCV-2) and porcine reproductive and respiratory syndrome 
      virus (PRRSV) through a longitudinal study in an integrated swine production 
      system (7 farms) experiencing postweaning multisystemic wasting syndrome (PMWS). 
      Risk factors for PCV-2 infection and for PCV-2 and PRRSV coinfection were also 
      evaluated. Fifteen sows from each herd and 4 non-cross-fostered piglets from each 
      sow were randomly selected at farrowing and ear-tagged at birth. Serum samples 
      were analyzed for antibodies to PCV-2 and for detection of the PCV-2 and PRRSV 
      genomes. Statistical analyses involved 2 approaches. The 1st approach 
      characterized the dynamics of PCV-2 infection and their relationship with PRRSV 
      infection. The 2nd approach analyzed the probability of being infected by PCV-2 
      or by both PCV-2 and PRRSV through a generalized linear mixed model incorporating 
      sow and farm characteristics. At the 1st sampling time (1 wk of age), there was a 
      significant relationship between sow PCV-2 infection and piglet PCV-2 infection 
      (P < 0.0001). The risk of PCV-2 and PRRSV coinfection was 1.85 times greater in 
      piglets from a sow with low titers of PCV-2 antibodies than in piglets from sows 
      with medium to high titers (P = 0.03) and was 2.54, 2.40, and 2.02 times greater, 
      respectively, in piglets from primiparous sows, PCV-2-infected sows, and farms in 
      an area of high pig density than in piglets from sows of higher parity (P = 
      0.004), noninfected sows (P = 0.04), and farms in a low-density area (P = 0.09).
FAU - Fraile, Lorenzo
AU  - Fraile L
AD  - Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat 
      Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. 
      lorenzo.fraile@cresa.uab.es
FAU - Calsamiglia, Maria
AU  - Calsamiglia M
FAU - Mateu, Enric
AU  - Mateu E
FAU - Espinal, Anna
AU  - Espinal A
FAU - Cuxart, Anna
AU  - Cuxart A
FAU - Seminati, Chiara
AU  - Seminati C
FAU - Martin, Marga
AU  - Martin M
FAU - Domingo, Mariano
AU  - Domingo M
FAU - Segales, Joaquim
AU  - Segales J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - Can J Vet Res
JT  - Canadian journal of veterinary research = Revue canadienne de recherche 
      veterinaire
JID - 8607793
RN  - 0 (Antibodies, Viral)
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - Antibodies, Viral/blood
MH  - Chi-Square Distribution
MH  - Circoviridae Infections/*epidemiology/immunology/*veterinary/virology
MH  - Circovirus/genetics/immunology/*isolation & purification
MH  - Female
MH  - Immunoenzyme Techniques/veterinary
MH  - Linear Models
MH  - Longitudinal Studies
MH  - Polymerase Chain Reaction/veterinary
MH  - Porcine Postweaning Multisystemic Wasting 
      Syndrome/*epidemiology/immunology/virology
MH  - Porcine Reproductive and Respiratory Syndrome/*epidemiology/immunology/virology
MH  - Porcine respiratory and reproductive syndrome 
      virus/genetics/immunology/*isolation & purification
MH  - Pregnancy
MH  - Prevalence
MH  - RNA, Viral/chemistry/genetics
MH  - Swine
PMC - PMC2757713
EDAT- 2010/01/05 06:00
MHDA- 2010/03/12 06:00
PMCR- 2010/01/01
CRDT- 2010/01/05 06:00
PHST- 2008/02/26 00:00 [received]
PHST- 2008/11/13 00:00 [accepted]
PHST- 2010/01/05 06:00 [entrez]
PHST- 2010/01/05 06:00 [pubmed]
PHST- 2010/03/12 06:00 [medline]
PHST- 2010/01/01 00:00 [pmc-release]
AID - cjvr_10_308 [pii]
PST - ppublish
SO  - Can J Vet Res. 2009 Oct;73(4):308-12.