PMID- 2004761 OWN - NLM STAT- MEDLINE DCOM- 19910423 LR - 20190903 IS - 0888-7543 (Print) IS - 0888-7543 (Linking) VI - 9 IP - 1 DP - 1991 Jan TI - Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1. PG - 200-3 AB - Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1. FAU - Mehrabian, M AU - Mehrabian M AD - Division of Cardiology, University of California, Los Angeles 90024. FAU - Sparkes, R S AU - Sparkes RS FAU - Mohandas, T AU - Mohandas T FAU - Fogelman, A M AU - Fogelman AM FAU - Lusis, A J AU - Lusis AJ LA - eng GR - HL30568/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Genomics JT - Genomics JID - 8800135 RN - 0 (Chemokine CCL2) RN - 0 (Chemotactic Factors) SB - IM GS - SCYA2 MH - Animals MH - Base Sequence MH - Chemokine CCL2 MH - Chemotactic Factors/*genetics MH - Chromosome Banding MH - Chromosome Mapping MH - *Chromosomes, Human, Pair 17 MH - Genes MH - Humans MH - Hybrid Cells MH - Mice MH - Molecular Sequence Data MH - Monocytes EDAT- 1991/01/01 00:00 MHDA- 1991/01/01 00:01 CRDT- 1991/01/01 00:00 PHST- 1991/01/01 00:00 [pubmed] PHST- 1991/01/01 00:01 [medline] PHST- 1991/01/01 00:00 [entrez] AID - 0888-7543(91)90239-B [pii] AID - 10.1016/0888-7543(91)90239-b [doi] PST - ppublish SO - Genomics. 1991 Jan;9(1):200-3. doi: 10.1016/0888-7543(91)90239-b.