PMID- 20061660
OWN - NLM
STAT- MEDLINE
DCOM- 20100315
LR  - 20191027
IS  - 2384-8553 (Electronic)
IS  - 0021-2571 (Linking)
VI  - 45
IP  - 4
DP  - 2009
TI  - Serum concentrations of beta-hexachlorocyclohexane in groups of the Italian 
      general population: a human biomonitoring study.
PG  - 401-8
AB  - Because of its persistence and toxicological profile, beta-hexachlorocyclohexane 
      (beta-HCH) has been proposed for inclusion in the Stockholm Convention on 
      persistent organic pollutants (POPs). Although the use of technical HCH, which is 
      the primary source of beta-HCH in the environment, has been banned in the EU in 
      1978 and progressively at a global level, beta-HCH is still detectable in the 
      general environment worldwide. Human exposure mostly occurs via food and may be 
      of concern in areas where illegal use and/or improper disposal of stockpiles 
      occurred and locally grown food is consumed. Exposure of the Italian general 
      population to beta-HCH has been poorly characterised. Lack of human biomonitoring 
      data severely hinders the ability to interpret potential increases in exposure 
      related to situations of environmental risk. We carried out a human biomonitoring 
      study aimed to provide baseline information on background exposure of the Italian 
      general population to this pollutant. For this purpose, we analysed 116 serum 
      samples from groups of subjects of both sex from the general population residing 
      in three Italian towns at different latitudes. Serum concentrations of beta-HCH 
      resulted to be comprised between 1.64 and 300 ng/g fat, with a median value of 
      18.0 ng/g fat and a 90th percentile of 65.9 ng/g fat. The serum concentrations 
      detected are in line with those detected in most Western European countries.
FAU - Ingelido, Anna Maria
AU  - Ingelido AM
AD  - Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di 
      Sanita, Rome, Italy.
FAU - Abballe, Annalisa
AU  - Abballe A
FAU - Marra, Valentina
AU  - Marra V
FAU - Valentini, Silvia
AU  - Valentini S
FAU - Ferro, Annamaria
AU  - Ferro A
FAU - Porpora, Maria Grazia
AU  - Porpora MG
FAU - Barbieri, Pietro Gino
AU  - Barbieri PG
FAU - De Felip, Elena
AU  - De Felip E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Italy
TA  - Ann Ist Super Sanita
JT  - Annali dell'Istituto superiore di sanita
JID - 7502520
RN  - 0 (Insecticides)
RN  - 0 (Pesticide Residues)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - YM80ODM9PD (beta-hexachlorocyclohexane)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Environmental Exposure
MH  - *Environmental Monitoring
MH  - Europe
MH  - Female
MH  - Hexachlorocyclohexane/*blood
MH  - Humans
MH  - Insecticides/*blood
MH  - Italy
MH  - Male
MH  - Middle Aged
MH  - Pesticide Residues
MH  - Sex Factors
MH  - Young Adult
EDAT- 2010/01/12 06:00
MHDA- 2010/03/17 06:00
CRDT- 2010/01/12 06:00
PHST- 2010/01/12 06:00 [entrez]
PHST- 2010/01/12 06:00 [pubmed]
PHST- 2010/03/17 06:00 [medline]
AID - 10.1590/s0021-25712009000400008 [doi]
PST - ppublish
SO  - Ann Ist Super Sanita. 2009;45(4):401-8. doi: 10.1590/s0021-25712009000400008.