PMID- 20078832
OWN - NLM
STAT- MEDLINE
DCOM- 20100428
LR  - 20100118
IS  - 1365-3016 (Electronic)
IS  - 0269-5022 (Linking)
VI  - 24
IP  - 1
DP  - 2010 Jan
TI  - Serum level of immunoglobulin E during pregnancy - does offspring sex matter?
PG  - 75-8
LID - 10.1111/j.1365-3016.2009.01092.x [doi]
AB  - We assessed maternal serum levels of total immunoglobulin E (IgE) in the first, 
      second and third trimester and changes in total IgE levels from first to third 
      trimester in relation to offspring sex. Within a cohort of 29 948 pregnant women, 
      392 women without a history of pre-eclampsia and with a liveborn child were 
      randomly selected. Information on offspring sex was obtained through linkage to 
      the Medical Birth Registry of Norway. Blood samples from each trimester were 
      analysed for total IgE concentration. Differences in mean levels according to 
      offspring sex were estimated and changes in total IgE levels from first to third 
      trimester were assessed. In all three trimesters there was a tendency of women 
      carrying a male fetus to have a higher mean total IgE level, but significant 
      statistical differences were not reached. The total IgE concentration decreased 
      during pregnancy, but the decrement was less in women carrying a male fetus 
      compared with those who carried a female fetus.
FAU - Loken, Mari Overn
AU  - Loken MO
AD  - Department of Obstetrics and Gynaecology and Medical Faculty Division, Akershus 
      University Hospital, University of Oslo, Oslo, Norway. mari.overn@studmed.uio.no
FAU - Jeansson, Stig
AU  - Jeansson S
FAU - Jenum, Pal A
AU  - Jenum PA
FAU - Eskild, Anne
AU  - Eskild A
LA  - eng
PT  - Journal Article
PL  - England
TA  - Paediatr Perinat Epidemiol
JT  - Paediatric and perinatal epidemiology
JID - 8709766
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - Pregnancy/*blood
MH  - Pregnancy Trimesters/blood
MH  - *Sex Factors
EDAT- 2010/01/19 06:00
MHDA- 2010/04/29 06:00
CRDT- 2010/01/19 06:00
PHST- 2010/01/19 06:00 [entrez]
PHST- 2010/01/19 06:00 [pubmed]
PHST- 2010/04/29 06:00 [medline]
AID - PPE1092 [pii]
AID - 10.1111/j.1365-3016.2009.01092.x [doi]
PST - ppublish
SO  - Paediatr Perinat Epidemiol. 2010 Jan;24(1):75-8. doi: 
      10.1111/j.1365-3016.2009.01092.x.