PMID- 20081177 OWN - NLM STAT- MEDLINE DCOM- 20100301 LR - 20120510 IS - 2042-7670 (Electronic) IS - 0042-4900 (Linking) VI - 166 IP - 3 DP - 2010 Jan 16 TI - Efficacy of combined porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae vaccination in piglets. PG - 70-4 LID - 10.1136/vr.c176 [doi] AB - Three vaccination challenge studies were performed to evaluate the impact on vaccine efficacy of combining porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae vaccines. Piglets were vaccinated with either a M hyopneumoniae bacterin, a modified live PRRSV vaccine based on a European-type PRRSV strain, or a combination of both vaccines, followed by experimental infection with either M hyopneumoniae or PRRSV. Vaccine efficacy was evaluated by assessing lung lesion scores for M hyopneumoniae and measuring viraemia for PRRSV. There were no significant differences between the protective efficacy of the combined vaccine protocol and the protective efficacy of the two single vaccines, indicating that PRRSV vaccination did not interfere with M hyopneumoniae vaccine efficacy and vice versa. FAU - Drexler, C S AU - Drexler CS AD - Intervet/Schering-Plough Animal Health, 5830 AA Boxmeer, The Netherlands. christa.drexler@intervet.com FAU - Witvliet, M H AU - Witvliet MH FAU - Raes, M AU - Raes M FAU - van de Laar, M AU - van de Laar M FAU - Eggen, A A S AU - Eggen AA FAU - Thacker, E L AU - Thacker EL LA - eng PT - Journal Article PL - England TA - Vet Rec JT - The Veterinary record JID - 0031164 RN - 0 (Bacterial Vaccines) RN - 0 (Vaccines, Attenuated) RN - 0 (Vaccines, Combined) RN - 0 (Viral Vaccines) SB - IM MH - Animals MH - Animals, Newborn MH - Bacterial Vaccines/*administration & dosage MH - Mycoplasma hyopneumoniae/*immunology MH - Pneumonia of Swine, Mycoplasmal/*prevention & control MH - Porcine Reproductive and Respiratory Syndrome/*prevention & control MH - Porcine respiratory and reproductive syndrome virus/*immunology MH - Random Allocation MH - Specific Pathogen-Free Organisms MH - Swine MH - Treatment Outcome MH - Vaccines, Attenuated MH - Vaccines, Combined MH - Viral Vaccines/*administration & dosage EDAT- 2010/01/19 06:00 MHDA- 2010/03/02 06:00 CRDT- 2010/01/19 06:00 PHST- 2010/01/19 06:00 [entrez] PHST- 2010/01/19 06:00 [pubmed] PHST- 2010/03/02 06:00 [medline] AID - 166/3/70 [pii] AID - 10.1136/vr.c176 [doi] PST - ppublish SO - Vet Rec. 2010 Jan 16;166(3):70-4. doi: 10.1136/vr.c176.