PMID- 20091182
OWN - NLM
STAT- MEDLINE
DCOM- 20100623
LR  - 20211020
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 108
IP  - 6
DP  - 2010 Apr
TI  - Influence of dietary carbohydrate intake on the free testosterone: cortisol ratio 
      responses to short-term intensive exercise training.
PG  - 1125-31
LID - 10.1007/s00421-009-1220-5 [doi]
AB  - This study examined the effect of dietary carbohydrate (CHO) consumption on the 
      free testosterone to cortisol (fTC) ratio during a short-term intense micro-cycle 
      of exercise training. The fTC ratio is a proposed biomarker for 
      overreaching-overtraining (i.e., training stress or imbalance) in athletes. The 
      ratio was studied in two groups, control-CHO (approximately 60% of daily intake, 
      n = 12) and low-CHO (approximately 30% of daily intake, n = 8), of male subjects 
      who performed three consecutive days of intensive training (approximately 70-75% 
      maximal oxygen consumption, 60 min per day) with a dietary intervention (on the 
      day before and during training). Resting, pre-exercise blood samples were 
      collected under standardized-controlled conditions before each day of training 
      (Pre 1, 2, 3) and on a fourth day after the micro-cycle (Rest). Bloods were 
      analyzed for free testosterone and cortisol via radioimmunoassay procedures. 
      Subjects performed no additional physical activity other than prescribed 
      training. Statistical analysis (ANCOVA) revealed the fTC ratio decreased 
      significantly (p < 0.01) from pre-study resting measurement (Pre 1) to the final 
      post-study resting measurement (Rest) in the low-CHO group (-43%), but no change 
      occurred (p > 0.05) in the control-CHO group (-3%). Findings suggest if the fTC 
      ratio is utilized as a marker of training stress or imbalance it is necessary for 
      a moderately high diet of CHO to be consumed to maintain validity of any observed 
      changes in the ratio value.
FAU - Lane, Amy R
AU  - Lane AR
AD  - Endocrine Section, Applied Physiology Laboratory, Department of Exercise and 
      Sport Science, University of North Carolina, Chapel Hill, NC 27599, USA.
FAU - Duke, Joseph W
AU  - Duke JW
FAU - Hackney, Anthony C
AU  - Hackney AC
LA  - eng
PT  - Journal Article
DEP - 20091220
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Dietary Carbohydrates)
RN  - 3XMK78S47O (Testosterone)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Dietary Carbohydrates/*metabolism
MH  - Eating/physiology
MH  - Exercise/*physiology
MH  - Humans
MH  - Hydrocortisone/*blood
MH  - Male
MH  - Physical Endurance/*physiology
MH  - Physical Exertion/*physiology
MH  - Physical Fitness/*physiology
MH  - Testosterone/*blood
MH  - Young Adult
EDAT- 2010/01/22 06:00
MHDA- 2010/06/24 06:00
CRDT- 2010/01/22 06:00
PHST- 2009/09/18 00:00 [accepted]
PHST- 2010/01/22 06:00 [entrez]
PHST- 2010/01/22 06:00 [pubmed]
PHST- 2010/06/24 06:00 [medline]
AID - 10.1007/s00421-009-1220-5 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2010 Apr;108(6):1125-31. doi: 10.1007/s00421-009-1220-5. Epub 
      2009 Dec 20.