PMID- 20092867
OWN - NLM
STAT- MEDLINE
DCOM- 20100310
LR  - 20161125
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 78
IP  - 10
DP  - 2010 Mar
TI  - Persistent organic pollutants (PCDD/Fs, dioxin-like PCBs, marker PCBs, and PBDEs) 
      in health supplements on the Spanish market.
PG  - 1256-62
LID - 10.1016/j.chemosphere.2009.12.038 [doi]
AB  - During the last years, consumption of health supplements has increased in our 
      society. They are recommended as an additional source of minerals, vitamins, 
      omega-3 and omega-6 fatty acids, in the diet. A lot of these supplements contain 
      oils among their components (fish oils or vegetable oils), especially those 
      recommended for their omega-3 content. Due to their persistence and lipophilic 
      characteristics, polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated 
      dibenzofurans (PCDFs), dioxin-like polychlorinated biphenyls (PCBs), marker PCBs, 
      and polybrominated diphenyl ethers (PBDEs) bioaccumulate in fat tissues, 
      especially in those animals, as fish, which show low metabolic capability. 
      Therefore, the consumption of nutritional supplements with oil components can 
      increase the intake of persistent organic pollutants (POPs) through the diet. The 
      aim of this study was to analyse 15 of these supplements commercialized in Spain 
      to determinate their POPs concentrations and their intake for their consumers. 
      Concentrations of POPs in the dietary supplements studied (PCDD/Fs: 0.04-2.4 pg 
      TEQ g(-1); dl-PCBs: 0.01-12.1 pg TEQ g(-1); marker PCBs: 0.17-116 ng g(-1); and 
      PBDEs: 0.07-18.2 ng g(-1)) were in the low-medium range of those reported in 
      literature for other countries. Vegetable oil and mineral-based supplements 
      showed concentrations of POPs clearly lower than those based on fish oil. Among 
      these, those based on cod liver oil presented the highest concentrations detected 
      in the study, exceeding the maximum levels established in European regulations 
      for marine oils for human consumption. In general, the intake of POPs via the 
      consumption of these supplements would be lower than the intake derived from fish 
      consumption.
CI  - Copyright (c) 2009 Elsevier Ltd. All rights reserved.
FAU - Marti, M
AU  - Marti M
AD  - Environmental Laboratory, Institut Quimic de Sarria (URL), Via Augusta 390, 
      Barcelona, Spain.
FAU - Ortiz, X
AU  - Ortiz X
FAU - Gasser, M
AU  - Gasser M
FAU - Marti, R
AU  - Marti R
FAU - Montana, M J
AU  - Montana MJ
FAU - Diaz-Ferrero, J
AU  - Diaz-Ferrero J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100125
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Benzofurans)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Fatty Acids, Omega-3)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Polymers)
RN  - 0 (Vitamins)
RN  - 0 (polychlorodibenzofuran)
RN  - 8001-69-2 (Cod Liver Oil)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Benzofurans/*analysis
MH  - Cod Liver Oil/chemistry
MH  - Dietary Supplements/*analysis
MH  - Environmental Pollutants/*analysis
MH  - Fatty Acids, Omega-3/chemistry
MH  - Halogenated Diphenyl Ethers/*analysis
MH  - Polychlorinated Biphenyls/*analysis
MH  - Polychlorinated Dibenzodioxins/*analogs & derivatives/analysis
MH  - Polymers/*analysis
MH  - Spain
MH  - Vitamins/chemistry
EDAT- 2010/01/23 06:00
MHDA- 2010/03/11 06:00
CRDT- 2010/01/23 06:00
PHST- 2009/09/07 00:00 [received]
PHST- 2009/12/09 00:00 [revised]
PHST- 2009/12/16 00:00 [accepted]
PHST- 2010/01/23 06:00 [entrez]
PHST- 2010/01/23 06:00 [pubmed]
PHST- 2010/03/11 06:00 [medline]
AID - S0045-6535(09)01461-1 [pii]
AID - 10.1016/j.chemosphere.2009.12.038 [doi]
PST - ppublish
SO  - Chemosphere. 2010 Mar;78(10):1256-62. doi: 10.1016/j.chemosphere.2009.12.038. 
      Epub 2010 Jan 25.