PMID- 20103039
OWN - NLM
STAT- MEDLINE
DCOM- 20100204
LR  - 20220330
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 149
IP  - 1
DP  - 2010 Jan
TI  - Spectral-domain optical coherence tomography: a comparison of modern 
      high-resolution retinal imaging systems.
PG  - 18-31
LID - 10.1016/j.ajo.2009.08.037 [doi]
AB  - PURPOSE: To provide a review of commercially available spectral-domain optical 
      coherence tomography (SD OCT) systems in clinical ophthalmology. DESIGN: 
      Perspective. METHODS: Review of current manufacturer information, selected 
      articles from the literature, and the authors' clinical experience. RESULTS: 
      Because the premise of SD OCT technology is the nonproprietary mathematical 
      formula of Fourier transformation, 9 different SD OCT systems currently are or 
      soon will be commercially available. Also demonstrated are Cirrus en face C-scan 
      visualization of photoreceptor attenuation resulting from acute zonal occult 
      outer retinopathy and Spectral OCT/scanning laser ophthalmoscopy microperimetric 
      analysis of a macular caldera lesion resulting from North Carolina macular 
      dystrophy. CONCLUSIONS: Advances in high-resolution imaging of the anterior and 
      posterior segment have revealed new in vivo details of anatomic, physiologic, and 
      pathologic data for the practice of ophthalmology. Compared with time-domain OCT, 
      SD OCT tends to derive increased retinal thickness and decreased nerve fiber 
      layer thickness measurements. This is likely because of increased depth of 
      resolution and greater volume of data acquired with each scan. Interdevice 
      comparison is not practical because of differences in individual segment boundary 
      algorithms. Improvements in photoreceptor inner segment-outer segment layer 
      visualization should aid our understanding of visual dysfunction in a variety of 
      retinal pathologic features. As the technology develops, SD OCT will continue to 
      provide new insights about ocular structure and disease.
CI  - Copyright 2010 Elsevier Inc. All rights reserved.
FAU - Kiernan, Daniel F
AU  - Kiernan DF
AD  - Department of Ophthalmology & Visual Sciences, Illinois Eye and Ear Infirmary, 
      University of Illinois at Chicago, Chicago, Illinois, USA.
FAU - Mieler, William F
AU  - Mieler WF
FAU - Hariprasad, Seenu M
AU  - Hariprasad SM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
MH  - *Diagnostic Techniques, Ophthalmological
MH  - Fourier Analysis
MH  - Humans
MH  - Retina/*pathology
MH  - Retinal Diseases/*diagnosis
MH  - Tomography, Optical Coherence/*methods
RF  - 52
EDAT- 2010/01/28 06:00
MHDA- 2010/02/05 06:00
CRDT- 2010/01/28 06:00
PHST- 2009/06/16 00:00 [received]
PHST- 2009/08/27 00:00 [revised]
PHST- 2009/08/28 00:00 [accepted]
PHST- 2010/01/28 06:00 [entrez]
PHST- 2010/01/28 06:00 [pubmed]
PHST- 2010/02/05 06:00 [medline]
AID - S0002-9394(09)00663-1 [pii]
AID - 10.1016/j.ajo.2009.08.037 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2010 Jan;149(1):18-31. doi: 10.1016/j.ajo.2009.08.037.