PMID- 20106487
OWN - NLM
STAT- MEDLINE
DCOM- 20100730
LR  - 20100419
IS  - 1532-8430 (Electronic)
IS  - 0022-0736 (Linking)
VI  - 43
IP  - 3
DP  - 2010 May-Jun
TI  - Ischemic ST-segment episodes during the initial 24 hours of ST elevation 
      myocardial infarction predict prognosis at 1 and 5 years.
PG  - 224-9
LID - 10.1016/j.jelectrocard.2009.12.010 [doi]
AB  - OBJECTIVES: The aims of the study were to assess the prognostic value of 
      recurrent ischemic episodes during the first 24 hours in ST elevation myocardial 
      infarction (STEMI) treated with thrombolysis and to explore those episodes as a 
      part of a low-risk prognostic feature. DESIGN: Two hundred twenty patients with 
      STEMI treated with thrombolysis were monitored for 24 hours with continuous 
      online vectorcardiography assessing ST vector changes to record recurrent 
      ischemic events. RESULTS: Ischemic events measured as an increase in ST-change 
      vector magnitude (STC-VM) more than 50 muV for at least 2 minutes during 4- to 
      24-hour predicted mortality in a 5-year follow-up based on a multivariable 
      analysis (hazard ratio, 1.18/episode; confidence interval, 1.01-1.37). The more 
      episodes there were, the worse the prognosis. A low-risk group with a 1-year 
      mortality of 1.9% could be identified. CONCLUSION: Continuous ST-segment 
      monitoring during the first 24 hours of a myocardial infarction is a valuable 
      tool for identifying high- and low-risk patients. The STC-VM events during 4 to 
      24 hours of the first day of a myocardial infarction predict mortality within 5 
      years.
CI  - Copyright (c) 2010 Elsevier Inc.. All rights reserved.
FAU - Ottander, Per
AU  - Ottander P
AD  - Department of Cardiology, Heart Centre, Umea University Hospital, Umea, Sweden. 
      per.ottander@vll.se
FAU - Nilsson, Johan B
AU  - Nilsson JB
FAU - Jensen, Steen M
AU  - Jensen SM
FAU - Naslund, Ulf
AU  - Naslund U
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100127
PL  - United States
TA  - J Electrocardiol
JT  - Journal of electrocardiology
JID - 0153605
SB  - IM
MH  - Aged
MH  - Electrocardiography/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/*mortality
MH  - Prevalence
MH  - Prognosis
MH  - Reproducibility of Results
MH  - Risk Assessment
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Survival Analysis
MH  - Survival Rate
MH  - Sweden/epidemiology
EDAT- 2010/01/29 06:00
MHDA- 2010/07/31 06:00
CRDT- 2010/01/29 06:00
PHST- 2009/10/12 00:00 [received]
PHST- 2010/01/29 06:00 [entrez]
PHST- 2010/01/29 06:00 [pubmed]
PHST- 2010/07/31 06:00 [medline]
AID - S0022-0736(09)00637-2 [pii]
AID - 10.1016/j.jelectrocard.2009.12.010 [doi]
PST - ppublish
SO  - J Electrocardiol. 2010 May-Jun;43(3):224-9. doi: 
      10.1016/j.jelectrocard.2009.12.010. Epub 2010 Jan 27.