PMID- 20111649
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20240322
IS  - 1738-5555 (Electronic)
IS  - 1738-5520 (Print)
IS  - 1738-5520 (Linking)
VI  - 40
IP  - 1
DP  - 2010 Jan
TI  - Long-term outcomes after an arterial switch operation for simple complete 
      transposition of the great arteries.
PG  - 23-30
LID - 10.4070/kcj.2010.40.1.23 [doi]
AB  - BACKGROUND AND OBJECTIVES: Although coronary artery obstruction, aortic 
      insufficiency (AI), and pulmonary stenosis (PS) have been reported after arterial 
      switch operation (ASO), limited long-term studies on ASO exist. Our study aimed 
      to examine long-term outcomes after ASO for simple complete transposition of the 
      great arteries (TGA). SUBJECTS AND METHODS: All 108 patients with simple complete 
      TGA who underwent ASO at Seoul National University Children's Hospital between 
      1987 and 2004 were enrolled. We retrospectively reviewed the patients' medical 
      records and the results of various functional and imaging studies. RESULTS: Among 
      108 cases of ASO for simple TGA, 96 have been followed-up through the present 
      time (mean follow-up duration was 11.7+/-8.6 years: range= 4 to 23 years). The 
      20-year rates of freedom from significant AI, PS, and coronary obstruction were 
      78.6%, 67.8%, and 95.8%, respectively. AI showed a tendency to progress as 
      follow-up time increased in 21.4% of the population studied (p=0.014); however, 
      AS, PS, and PI showed no such progression. Late coronary artery occlusion was not 
      associated with the initial coronary arterial pattern. Re-operations were done 
      for 13 patients (13.5%) at an average of 8+/-4.3 years after ASO. The survival 
      rate was 96%, while the re-operation-free was 90% at 10 years and 83% at 20 
      years. Most patients showed normal physical growth with good activity 98%; New 
      York Heart Association (NYHA) class 1 activity and normal development (96%). 
      CONCLUSION: Although most patients showed normal physical growth and development 
      after successful ASO, meticulous long-term follow-up is necessary because of 
      progressive AI and coronary complications.
FAU - Choi, Byeong Sam
AU  - Choi BS
AD  - Division of Cardiology, Department of Pediatrics, Seoul National University 
      Children's Hospital, Seoul National University College of Medicine, Seoul, Korea.
FAU - Kwon, Bo Sang
AU  - Kwon BS
FAU - Kim, Gi Beom
AU  - Kim GB
FAU - Bae, Eun Jung
AU  - Bae EJ
FAU - Noh, Chung Il
AU  - Noh CI
FAU - Choi, Jung Yun
AU  - Choi JY
FAU - Yun, Yong Soo
AU  - Yun YS
FAU - Kim, Woong Han
AU  - Kim WH
FAU - Lee, Jeong Ryul
AU  - Lee JR
FAU - Kim, Yong Jin
AU  - Kim YJ
LA  - eng
PT  - Journal Article
DEP - 20100127
PL  - Korea (South)
TA  - Korean Circ J
JT  - Korean circulation journal
JID - 101247141
PMC - PMC2812794
OTO - NOTNLM
OT  - Aortic valve insufficiency
OT  - Coronary arteries
OT  - Outcomes assessment, patient
OT  - Stenosis, pulmonary
OT  - Transposition of great vessels
EDAT- 2010/01/30 06:00
MHDA- 2010/01/30 06:01
PMCR- 2010/01/01
CRDT- 2010/01/30 06:00
PHST- 2009/05/07 00:00 [received]
PHST- 2009/07/09 00:00 [revised]
PHST- 2009/07/14 00:00 [accepted]
PHST- 2010/01/30 06:00 [entrez]
PHST- 2010/01/30 06:00 [pubmed]
PHST- 2010/01/30 06:01 [medline]
PHST- 2010/01/01 00:00 [pmc-release]
AID - 10.4070/kcj.2010.40.1.23 [doi]
PST - ppublish
SO  - Korean Circ J. 2010 Jan;40(1):23-30. doi: 10.4070/kcj.2010.40.1.23. Epub 2010 Jan 
      27.