PMID- 20113327
OWN - NLM
STAT- MEDLINE
DCOM- 20100920
LR  - 20161125
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 27
IP  - 3
DP  - 2010 Mar
TI  - Echocardiographic evaluation of right ventricular function in patients with acute 
      pulmonary embolism: a study using tricuspid annular motion.
PG  - 286-93
LID - 10.1111/j.1540-8175.2009.01015.x [doi]
AB  - Assessment of right ventricular (RV) function is a challenge due to complex 
      anatomy. We studied systolic and diastolic tricuspid annular excursion and 
      longitudinal RV fractional shortening as geometry-independent measures in 
      patients with acute pulmonary embolism (PE). Forty patients with PE were studied 
      within 24 hours after admission and after 3 months, and compared to 23 healthy 
      subjects used as controls. We recorded tricuspid annular plane systolic (TAPSE) 
      and diastolic (TAPDE) excursion from the four-chamber view and calculated RV 
      fractional shortening as TAPSE/RV diastolic length. The diastolic RV function was 
      defined as the ratio of the amplitude of tricuspid annular plane excursion during 
      atrial systole to total tricuspid annular plane diastolic excursion (atrial/total 
      TAPDE). In the acute stage, the TAPSE was decreased in PE compared to healthy 
      subjects (19 +/- 5 vs. 26 +/- 4 mm, P < 0.001), with greater reduction in 
      patients with increased, compared to normal, RV pressure (16.6 +/- 5 vs. 20.5 +/- 
      5 mm, P < 0.05). The atrial/total TAPDE was increased in patients compared to 
      healthy subjects (47 +/- 13% vs. 38 +/- 7%, P < 0.001) and normalized during the 
      follow-up. Although the patients were asymptomatic after 3 months, the TAPSE 
      recovered incompletely as compared to healthy subjects (21.4 +/- 4 vs. 26 +/- 4 
      mm, P < 0.001). Both systolic and diastolic RV function are impaired in acute PE. 
      Diastolic function recovers faster than systolic; therefore, the atrial 
      contribution to RV filling may be a useful measure to follow changes in diastolic 
      function in PE.
FAU - Rydman, Riikka
AU  - Rydman R
AD  - Section of Clinical Physiology, Department of Molecular Medicine and Surgery, 
      Karolinska University Hospital, SE-171 76 Stockholm, Sweden. 
      riikka.rydman@karolinska.se
FAU - Soderberg, Marten
AU  - Soderberg M
FAU - Larsen, Flemming
AU  - Larsen F
FAU - Caidahl, Kenneth
AU  - Caidahl K
FAU - Alam, Mahbubul
AU  - Alam M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100122
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Diastole
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Embolism/*diagnostic imaging/*physiopathology
MH  - Reference Standards
MH  - Systole
MH  - Tricuspid Valve/*diagnostic imaging/physiopathology
MH  - Ventricular Dysfunction, Right/*diagnostic imaging/*physiopathology
MH  - *Ventricular Function, Right
EDAT- 2010/02/02 06:00
MHDA- 2010/09/21 06:00
CRDT- 2010/02/02 06:00
PHST- 2010/02/02 06:00 [entrez]
PHST- 2010/02/02 06:00 [pubmed]
PHST- 2010/09/21 06:00 [medline]
AID - ECHO1015 [pii]
AID - 10.1111/j.1540-8175.2009.01015.x [doi]
PST - ppublish
SO  - Echocardiography. 2010 Mar;27(3):286-93. doi: 10.1111/j.1540-8175.2009.01015.x. 
      Epub 2010 Jan 22.