PMID- 20113951
OWN - NLM
STAT- MEDLINE
DCOM- 20100311
LR  - 20110922
IS  - 1532-2750 (Electronic)
IS  - 1098-612X (Linking)
VI  - 12
IP  - 2
DP  - 2010 Feb
TI  - Immunohistological evaluation of feline herpesvirus-1 infection in feline 
      eosinophilic dermatoses or stomatitis.
PG  - 72-9
LID - 10.1016/j.jfms.2009.12.013 [doi]
AB  - This study used immunohistochemistry (IHC) and histopathology to evaluate the 
      presence of feline herpesvirus-1 (FHV-1) in feline cases of 'eosinophilic 
      granuloma complex' (EGC) or other eosinophilic dermatoses or stomatitis, 
      diagnosed at the Veterinary Pathology Diagnostic Service, University of Sydney 
      between January 1996 and June 2008. Two of the 30 cases (6.6%) examined showed 
      positive immunoreactivity to FHV-1 using IHC. Intranuclear inclusion bodies were 
      also detected on histopathological examination of haematoxylin and eosin stained 
      sections of both cases but were very difficult to find. Therefore, FHV-1 is 
      uncommonly associated with EGC or other eosinophilic dermatoses or stomatitis in 
      Sydney. However, misdiagnosis as an EGC lesion or other eosinophilic dermatoses 
      may occur if inclusion bodies are overlooked or absent on histopathology and this 
      may significantly decrease the chance of a favourable treatment outcome. FHV-1 
      should be considered in cats with severe ulcerative cutaneous or oral lesions, 
      unresponsive to corticosteroid treatment, with or without concurrent or 
      historical signs of upper respiratory tract or ocular disease more typical of 
      FHV-1. IHC may be helpful in differentiating FHV-1 dermatitis or stomatitis from 
      other eosinophilic lesions, which is of vital clinical and therapeutic 
      importance.
CI  - Crown Copyright 2009. Published by Elsevier Ltd. All rights reserved.
FAU - Lee, Meichet
AU  - Lee M
AD  - The University of Sydney, NSW 2006, Australia.
FAU - Bosward, Katrina L
AU  - Bosward KL
FAU - Norris, Jacqueline M
AU  - Norris JM
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Feline Med Surg
JT  - Journal of feline medicine and surgery
JID - 100897329
SB  - IM
EIN - J Feline Med Surg. 2010 Apr;12(4):364
MH  - Alphaherpesvirinae/immunology/isolation & purification
MH  - Animals
MH  - Cat Diseases/*pathology
MH  - Cats
MH  - Eosinophilic Granuloma/pathology/*veterinary
MH  - Female
MH  - Herpesviridae Infections/pathology/*veterinary
MH  - Immunohistochemistry/veterinary
MH  - Male
MH  - Skin Diseases/pathology/*veterinary
MH  - Stomatitis/pathology/*veterinary
EDAT- 2010/02/02 06:00
MHDA- 2010/03/12 06:00
CRDT- 2010/02/02 06:00
PHST- 2009/06/16 00:00 [accepted]
PHST- 2010/02/02 06:00 [entrez]
PHST- 2010/02/02 06:00 [pubmed]
PHST- 2010/03/12 06:00 [medline]
AID - S1098-612X(09)00339-8 [pii]
AID - 10.1016/j.jfms.2009.12.013 [doi]
PST - ppublish
SO  - J Feline Med Surg. 2010 Feb;12(2):72-9. doi: 10.1016/j.jfms.2009.12.013.