PMID- 20115935 OWN - NLM STAT- MEDLINE DCOM- 20100423 LR - 20161125 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 86 Suppl 1 DP - 2009 Dec TI - Contrast-induced nephropathy in patients with type 2 diabetes during coronary angiography: risk-factors and prognostic value. PG - S63-9 LID - 10.1016/S0168-8227(09)70012-9 [doi] AB - AIMS: To determine risk factors, prognostic, value prevention of development of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: We have retrospectively analyzed the incidence of CIN developed after PCI in 151 patients T2DM and 50 patients without diabetes. All patients were subjected to thorough clinical examination (including serum creatinine level before and 48 hours after intervention). RESULTS: CIN developed more frequently after PCI in patients with T2DM than in patients of the same age without diabetes at the same baseline renal function, volume of contrast media and hydration status. The risk of developing CIN in patients with T2DM is associated with: heart failure, anemia, volume of contrast media, diuretics use in the peri-procedure period, multiple coronary artery disease, need of interventional procedures. TIDM patients with CIN had faster decline of renal function, more often developed cardiovascular diseases and had lower 24 month survival rate. CONCLUSIONS: High risk of CIN development and its prognostic significance in patients with T2DM determine the necessity of individually evaluated risks for preventive measures during contrast media interventions. CI - Copyright 2009 Elsevier Ireland Ltd. All rights reserved. FAU - Zaytseva, Natalia V AU - Zaytseva NV AD - National Endocrinology Research Center, Moscow, Russian Federation. FAU - Shamkhalova, Minara S AU - Shamkhalova MS FAU - Shestakova, Marina V AU - Shestakova MV FAU - Matskeplishvili, Simon T AU - Matskeplishvili ST FAU - Tugeeva, Elvina F AU - Tugeeva EF FAU - Buziashvili, Ury I AU - Buziashvili UI FAU - Deev, Alexandr D AU - Deev AD FAU - Dedov, Ivan I AU - Dedov II LA - eng PT - Journal Article PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 RN - 0 (Contrast Media) RN - 0 (Lipids) SB - IM MH - Contrast Media/*adverse effects MH - Coronary Angiography/*adverse effects MH - Diabetes Mellitus, Type 2/blood/complications/*diagnostic imaging/physiopathology MH - Diabetic Nephropathies/*epidemiology MH - Female MH - Humans MH - Lipids/blood MH - Male MH - Middle Aged MH - Prognosis MH - Retrospective Studies MH - Risk Assessment MH - Risk Factors MH - Stroke Volume EDAT- 2010/02/02 06:00 MHDA- 2010/04/24 06:00 CRDT- 2010/02/02 06:00 PHST- 2010/02/02 06:00 [entrez] PHST- 2010/02/02 06:00 [pubmed] PHST- 2010/04/24 06:00 [medline] AID - S0168-8227(09)70012-9 [pii] AID - 10.1016/S0168-8227(09)70012-9 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2009 Dec;86 Suppl 1:S63-9. doi: 10.1016/S0168-8227(09)70012-9.