PMID- 20136711
OWN - NLM
STAT- MEDLINE
DCOM- 20100603
LR  - 20161018
IS  - 0891-6640 (Print)
IS  - 0891-6640 (Linking)
VI  - 24
IP  - 2
DP  - 2010 Mar-Apr
TI  - Ability of a 5-minute electrocardiography (ECG) for predicting arrhythmias in 
      Doberman Pinschers with cardiomyopathy in comparison with a 24-hour ambulatory 
      ECG.
PG  - 367-71
LID - 10.1111/j.1939-1676.2010.0477.x [doi]
AB  - BACKGROUND: Ventricular premature contractions (VPCs) are common in the occult 
      stage of cardiomyopathy in Doberman Pinschers. Although the gold standard for 
      detecting arrhythmia is the 24-hour ambulatory electrocardiography (ECG) 
      (Holter), this method is more expensive, time-consuming and often not as readily 
      available as common ECG. OBJECTIVES: Comparison of 5-minute ECGs with Holter 
      examinations. ANIMALS: Eight hundred and seventy-five 5-minute ECGs and Holter 
      examinations of 431 Doberman Pinschers. METHODS: Each examination included a 
      5-minute ECG and Holter examination. A cut-off value of > 100 VPCs/24 hours using 
      Holter was considered diagnostic for the presence of cardiomyopathy. Statistical 
      evaluation included calculation of sensitivity, specificity, positive predictive 
      value, and negative predictive value. RESULTS: Holter examinations revealed > 100 
      VPCs/24 hours in 204/875 examinations. At least 1 VPC during a 5-minute ECG was 
      detected in 131 (64.2%) of these 204 examinations. No VPCs were found in the 
      5-minute ECG in 73 (35.8%) examinations of affected Doberman Pinschers. A 
      5-minute ECG with at least 1 VPC as cut-off had a sensitivity of 64.2%, a 
      specificity of 96.7%, a positive predictive value of 85.6% and a negative 
      predictive value of 89.9% for the presence of > 100 VPCs/24 hours. CONCLUSIONS 
      AND CLINICAL IMPORTANCE: A 5-minute ECG is a rather insensitive method for 
      detecting arrhythmias in Doberman Pinschers. However, the occurrence of at least 
      1 VPC in 5 minutes strongly warrants further examination of the dog, because 
      specificity (96.7%) and positive predictive value (85.6%) are high and could 
      suggest occult cardiomyopathy.
FAU - Wess, G
AU  - Wess G
AD  - Clinic of Small Animal Medicine, LMU University, Munich, Germany. gwess@lmu.de
FAU - Schulze, A
AU  - Schulze A
FAU - Geraghty, N
AU  - Geraghty N
FAU - Hartmann, K
AU  - Hartmann K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Vet Intern Med
JT  - Journal of veterinary internal medicine
JID - 8708660
SB  - IM
MH  - Animals
MH  - Cardiomyopathy, Dilated/complications/*veterinary
MH  - Dog Diseases/*diagnosis
MH  - Dogs
MH  - Electrocardiography/*veterinary
MH  - Female
MH  - Male
MH  - Predictive Value of Tests
MH  - Ventricular Premature Complexes/diagnosis/*veterinary
EDAT- 2010/02/09 06:00
MHDA- 2010/06/04 06:00
CRDT- 2010/02/09 06:00
PHST- 2010/02/09 06:00 [entrez]
PHST- 2010/02/09 06:00 [pubmed]
PHST- 2010/06/04 06:00 [medline]
AID - JVIM477 [pii]
AID - 10.1111/j.1939-1676.2010.0477.x [doi]
PST - ppublish
SO  - J Vet Intern Med. 2010 Mar-Apr;24(2):367-71. doi: 
      10.1111/j.1939-1676.2010.0477.x.