PMID- 20137412
OWN - NLM
STAT- MEDLINE
DCOM- 20111115
LR  - 20100208
IS  - 0412-4081 (Print)
IS  - 0412-4081 (Linking)
VI  - 45
IP  - 11
DP  - 2009 Nov
TI  - [Thickness of the retinal nerve fiber layer in unilateral amblyopic patients with 
      high myopia in children].
PG  - 966-70
AB  - OBJECTIVE: To investigate the retina nerve fiber layer (RNFL) thickness in 
      unilateral amblyopic patients with high myopia. METHODS: Twenty-three cases (23 
      eyes) with unilateral high myopia amblyopia were tested by GD(X) ECC with laser 
      polarized light scans in the posterior pole of retina, to measure the relative 
      RNFL thickness according to papilla optical as a center, 3.2 mm as the diameter 
      of outer ring, 2.4 mm as the diameter of inner ring. The relative RNFL thickness 
      of high myopia amblyopia was compared with fellow eyes, normal eyes and high 
      myopia respectively and statistics analysis. RESULTS: TSNIT average, superior 
      average and inferior average of RNFL in high myopia amblyopia became thinning 
      (56.39 +/- 5.69, 68.30 +/- 10.16, 67.34 +/- 5.83), it showed statistically 
      differences when compared with fellow eyes (t = 2.090, 2.243, 4.236) and normal 
      eyes (t = 3.087, 1.025, 3.481) (P < 0.05). RNFL parameters were no statistically 
      significant differences between high myopia amblyopia and simple high myopia (t = 
      0.872, 0.297, 0.658; P > 0.05). TSNIT average decreases with axial length in high 
      myopia amblyopia and high myopia, there was inverse linear correlation between 
      RNFL thickness and axial length (r = -0.462, -0.395; P < 0.05). CONCLUSIONS: The 
      RNFL thickness of unilateral high myopia amblyopia of children was thinner than 
      normal, but there wasn't obvious compared with simple high myopia. The reasons 
      for decreased best corrected vision of unilateral high myopia amblyopia in 
      children still need further research.
FAU - Xiao, Man-Yi
AU  - Xiao MY
AD  - Department of Ophthalmology, The Second Xiangya Hospital of Central South 
      University, Changsha 410011, China. xiaomanyi2000@yahoo.com.cn
FAU - Hua, Shan
AU  - Hua S
FAU - Tang, Luo-Sheng
AU  - Tang LS
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Yan Ke Za Zhi
JT  - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
JID - 16210540R
SB  - IM
MH  - Adolescent
MH  - Amblyopia/*pathology
MH  - Case-Control Studies
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Male
MH  - Myopia/*pathology
MH  - Nerve Fibers/*pathology
MH  - Optic Nerve/pathology
MH  - Retina/*pathology
EDAT- 2010/02/09 06:00
MHDA- 2011/11/16 06:00
CRDT- 2010/02/09 06:00
PHST- 2010/02/09 06:00 [entrez]
PHST- 2010/02/09 06:00 [pubmed]
PHST- 2011/11/16 06:00 [medline]
PST - ppublish
SO  - Zhonghua Yan Ke Za Zhi. 2009 Nov;45(11):966-70.