PMID- 20144326 OWN - NLM STAT- MEDLINE DCOM- 20100602 LR - 20211020 IS - 1932-2968 (Electronic) IS - 1932-2968 (Linking) VI - 3 IP - 4 DP - 2009 Jul 1 TI - Waist circumference threshold values for type 2 diabetes risk. PG - 761-9 AB - Adult gains in body weight, excess adiposity, and intra-abdominal fat have each been associated with risk for type 2 diabetes mellitus (T2DM), forming the basis for preventive medicine guidelines and actuarial predictions using practical indices of weight (e.g., body mass index [BMI]) and waist circumference (WC). As obesity-related disease spreads beyond affluent western countries, application of WC thresholds to other populations has highlighted issues of their generalizability. For example, U.S. national health goals based on BMI < 25 kg/m(2) and WC < 89 cm (women) and <102 cm (men) differ considerably with a recent law in Japan mandating intervention for older adults with WC exceeding 90 cm (women) and 85 cm (men). The U.S. military has also faced issues of generalizability of WC-based adiposity standards that are fair and achievable. Data from many studies indicate that WC is a reliable biomarker for T2DM risk, suggesting that, for adult men and women, action thresholds should be more stringent than current U.S. guidelines, and it would not be harmful to set worldwide targets somewhere below 90 cm for men and women, regardless of weight status. Medical technology has provided many great insights into disease, including modern imaging technologies that have differentiated fat depots that have the greatest influence on T2DM, but ultimately, an inexpensive measuring tape provides the most useful and cost-effective preventive measure for T2DM today. At some point in the future, a Star Trek-like abdominal body fat "tricorder" noninvasive assessment of tissue composition may provide an advantage over abdominal girth. CI - Copyright 2009 Diabetes Technology Society. FAU - Friedl, Karl E AU - Friedl KE AD - Telemedicine and Advanced Technology Research Center, US Army Medical Research and Materiel Command, Fort Detrick, Maryland 21702-5012, USA. LA - eng PT - Journal Article PT - Review DEP - 20090701 PL - United States TA - J Diabetes Sci Technol JT - Journal of diabetes science and technology JID - 101306166 SB - IM MH - Adult MH - Body Composition MH - Body Mass Index MH - Diabetes Mellitus, Type 2/*prevention & control MH - Female MH - Humans MH - Japan MH - Male MH - Risk MH - Risk Factors MH - *Waist Circumference PMC - PMC2769976 EDAT- 2010/02/11 06:00 MHDA- 2010/06/03 06:00 PMCR- 2010/07/01 CRDT- 2010/02/11 06:00 PHST- 2010/02/11 06:00 [entrez] PHST- 2010/02/11 06:00 [pubmed] PHST- 2010/06/03 06:00 [medline] PHST- 2010/07/01 00:00 [pmc-release] AID - dst.3.4.0761 [pii] AID - 10.1177/193229680900300424 [doi] PST - epublish SO - J Diabetes Sci Technol. 2009 Jul 1;3(4):761-9. doi: 10.1177/193229680900300424.