PMID- 20146306 OWN - NLM STAT- MEDLINE DCOM- 20100618 LR - 20101118 IS - 1522-726X (Electronic) IS - 1522-1946 (Linking) VI - 75 IP - 5 DP - 2010 Apr 1 TI - Arterial access and door-to-balloon times for primary percutaneous coronary intervention in patients presenting with acute ST-elevation myocardial infarction. PG - 695-9 LID - 10.1002/ccd.22373 [doi] AB - OBJECTIVES: This study compares the transradial versus the transfemoral approach for time to intervention for patients presenting with ST elevation myocardial infarction (STEMI). BACKGROUND: Survival following STEMI is associated with reperfusion times (door-to-balloon; D2B). For patients undergoing primary PCI for acute STEMI, potential effects of transradial approach (r-PCI) as compared with the femoral artery approach (f-PCI) on D2B times have not been extensively studied. METHODS: Consecutive patients presenting with STEMI at a tertiary care medical center were enrolled in a comprehensive-Heart Alert program (HA) and included in this analysis. Time parameters measured included: door-to-ECG, ECG-to-HA activation, HA activation-to-cath lab team arrival, patient arrival in cath lab to arterial access, and arterial access-to-balloon inflation. RESULTS: Of 240 total patients, 205 underwent successful PCI (n = 124 r-PCI; n = 116 f-PCI). No significant difference was observed in the pre-cath lab times. Mean case start times for r-PCI took significantly longer (12.5 +/- 5.4 min vs. 10.5 +/- 5.7 min, P = 0.005) due to patient preparation. Once arterial access was obtained, balloon inflation occurred faster in the r-PCI group (18.3 vs. 24.1 min; P < 0.001). Total time from patient arrival to the cardiac cath lab to PCI was reduced in the r-PCI as compared to the f-PCI group (28.4 vs. 32.7 min, P = 0.01). There was a small but statistical difference in D2B time (r-PCI 76.4 min vs. f-PCI 86.5 min P = 0.008). CONCLUSIONS: Patients presenting with STEMI can undergo successful PCI via radial artery approach without compromise in D2B times as compared to femoral artery approach. CI - (c) 2009 Wiley-Liss, Inc. FAU - Weaver, Aaron N AU - Weaver AN AD - Heart and Vascular Institute, Penn State University, Hershey Medical Center, Hershey, Pennsylvania, USA. aweaver@hmc.psu.edu FAU - Henderson, Rick A AU - Henderson RA FAU - Gilchrist, Ian C AU - Gilchrist IC FAU - Ettinger, Steven M AU - Ettinger SM LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Catheter Cardiovasc Interv JT - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JID - 100884139 SB - IM CIN - Catheter Cardiovasc Interv. 2010 Apr 1;75(5):700. PMID: 20333670 MH - Academic Medical Centers MH - Aged MH - Angioplasty, Balloon, Coronary/adverse effects/*methods/mortality MH - Chi-Square Distribution MH - Clinical Competence MH - Databases as Topic MH - Electrocardiography MH - *Emergency Medical Services MH - Female MH - *Femoral Artery MH - *Health Services Accessibility MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/diagnosis/mortality/*therapy MH - Prospective Studies MH - Quality of Health Care MH - *Radial Artery MH - Risk Assessment MH - Time Factors MH - *Transportation of Patients MH - Treatment Outcome EDAT- 2010/02/11 06:00 MHDA- 2010/06/19 06:00 CRDT- 2010/02/11 06:00 PHST- 2010/02/11 06:00 [entrez] PHST- 2010/02/11 06:00 [pubmed] PHST- 2010/06/19 06:00 [medline] AID - 10.1002/ccd.22373 [doi] PST - ppublish SO - Catheter Cardiovasc Interv. 2010 Apr 1;75(5):695-9. doi: 10.1002/ccd.22373.