PMID- 20147316 OWN - NLM STAT- MEDLINE DCOM- 20100910 LR - 20211020 IS - 1742-5662 (Electronic) IS - 1742-5689 (Print) IS - 1742-5662 (Linking) VI - 7 IP - 48 DP - 2010 Jul 6 TI - Transferring vertically aligned carbon nanotubes onto a polymeric substrate using a hot embossing technique for microfluidic applications. PG - 1129-33 LID - 10.1098/rsif.2009.0520 [doi] AB - We explored the hot embossing method for transferring vertically aligned carbon nanotubes (CNTs) into microfluidic channels, fabricated on poly-methyl-methacrylate (PMMA). Patterned and unpatterned CNTs were synthesized by microwave plasma-enhanced chemical vapour deposition on silicon to work as a stamp. For hot embossing, 115 degrees C and 1 kN force for 2 min were found to be the most suitable parameters for the complete transfer of aligned CNTs on the PMMA microchannel. Raman and SEM studies were used to analyse the microstructure of CNTs before and after hot embossing. The PMMA microparticles with dimensions (approx. 10 microm in diameter) similar to red blood cells were successfully filtered using laminar flow through these microfluidic channels. Finally, a microfluidic-based point-of-care device for blood filtration and detection of bio-molecules is drawn schematically. FAU - Mathur, A AU - Mathur A AD - Nanotechnology and Integrated Bio-Engineering Centre, School of Electrical and Mechanical Engineering, University of Ulster, Newtownabbey BT37 0QB, UK. FAU - Roy, S S AU - Roy SS FAU - McLaughlin, J A AU - McLaughlin JA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100210 PL - England TA - J R Soc Interface JT - Journal of the Royal Society, Interface JID - 101217269 RN - 0 (Gases) RN - 0 (Nanotubes, Carbon) RN - 0 (Polymers) RN - 9011-14-7 (Polymethyl Methacrylate) RN - Z4152N8IUI (Silicon) SB - IM MH - Evaluation Studies as Topic MH - Gases MH - Hot Temperature MH - Microfluidics/*instrumentation MH - Nanotubes, Carbon/*chemistry MH - Polymers MH - Polymethyl Methacrylate/chemistry MH - Silicon PMC - PMC2880084 EDAT- 2010/02/12 06:00 MHDA- 2010/09/11 06:00 PMCR- 2011/07/06 CRDT- 2010/02/12 06:00 PHST- 2010/02/12 06:00 [entrez] PHST- 2010/02/12 06:00 [pubmed] PHST- 2010/09/11 06:00 [medline] PHST- 2011/07/06 00:00 [pmc-release] AID - rsif.2009.0520 [pii] AID - rsif20090520 [pii] AID - 10.1098/rsif.2009.0520 [doi] PST - ppublish SO - J R Soc Interface. 2010 Jul 6;7(48):1129-33. doi: 10.1098/rsif.2009.0520. Epub 2010 Feb 10.