PMID- 20164210
OWN - NLM
STAT- MEDLINE
DCOM- 20100823
LR  - 20220408
IS  - 1532-2548 (Electronic)
IS  - 0032-0889 (Print)
IS  - 0032-0889 (Linking)
VI  - 152
IP  - 4
DP  - 2010 Apr
TI  - Identification of microRNAs involved in pathogen-associated molecular 
      pattern-triggered plant innate immunity.
PG  - 2222-31
LID - 10.1104/pp.109.151803 [doi]
AB  - Pathogen-associated molecular patterns (PAMPs) trigger plant defenses when 
      perceived by surface-localized immune receptors. PAMP-triggered immunity (PTI) 
      plays a vital role in the resistance of plants to numerous potential pathogens. 
      MicroRNA (miRNA) biogenesis is known to be important for PTI, but miRNA species 
      involved in this process have not been fully explored. Here we show that the 
      Arabidopsis (Arabidopsis thaliana) miRNA effector protein, Argonaute1 (AGO1), is 
      required for a number of PTI responses including PAMP-induced callose deposition, 
      gene expression, and seedling growth inhibition. Deep sequencing of AGO1-bound 
      small RNAs led to the identification of a number of miRNAs that are up- or 
      down-regulated by flg22, a well-studied PAMP. Overexpression of selected miRNAs 
      in stable transgenic plants demonstrated that miR160a positively regulate 
      PAMP-induced callose deposition, whereas miR398b and miR773 negatively regulate 
      PAMP-induced callose deposition and disease resistance to bacteria, suggesting a 
      complexity of the miRNA regulation in plant innate immunity.
FAU - Li, Yan
AU  - Li Y
AD  - State Key Laboratory of Plant Physiology and Biochemistry, College of Biological 
      Sciences, China Agricultural University, Beijing 100094, China.
FAU - Zhang, QingQing
AU  - Zhang Q
FAU - Zhang, Jiangguang
AU  - Zhang J
FAU - Wu, Liang
AU  - Wu L
FAU - Qi, Yijun
AU  - Qi Y
FAU - Zhou, Jian-Min
AU  - Zhou JM
LA  - eng
SI  - GDB/GSE20448
SI  - GDB/GSM512702
SI  - GDB/GSM512703
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100217
PL  - United States
TA  - Plant Physiol
JT  - Plant physiology
JID - 0401224
RN  - 0 (MicroRNAs)
SB  - IM
MH  - Arabidopsis/*immunology
MH  - *Immunity, Innate
MH  - MicroRNAs/*metabolism
MH  - Molecular Sequence Data
MH  - Plants/*immunology/microbiology
PMC - PMC2850012
EDAT- 2010/02/19 06:00
MHDA- 2010/08/24 06:00
PMCR- 2011/04/01
CRDT- 2010/02/19 06:00
PHST- 2010/02/19 06:00 [entrez]
PHST- 2010/02/19 06:00 [pubmed]
PHST- 2010/08/24 06:00 [medline]
PHST- 2011/04/01 00:00 [pmc-release]
AID - pp.109.151803 [pii]
AID - 151803 [pii]
AID - 10.1104/pp.109.151803 [doi]
PST - ppublish
SO  - Plant Physiol. 2010 Apr;152(4):2222-31. doi: 10.1104/pp.109.151803. Epub 2010 Feb 
      17.