PMID- 20171855
OWN - NLM
STAT- MEDLINE
DCOM- 20111219
LR  - 20161125
IS  - 1590-3729 (Electronic)
IS  - 0939-4753 (Linking)
VI  - 21
IP  - 8
DP  - 2011 Aug
TI  - Dietary antioxidant capacity is inversely associated with diabetes biomarkers: 
      the ATTICA study.
PG  - 561-7
LID - 10.1016/j.numecd.2009.11.005 [doi]
AB  - BACKGROUND AND AIMS: Elevated dietary antioxidant activity has been regarded as 
      providing potential benefits to health. The present work aimed at evaluating the 
      association of glycemic indices with total dietary antioxidant capacity in 
      healthy adults. METHODS AND RESULTS: The ATTICA study consisted of men and women, 
      randomly selected from all areas of Attica region in Greece. In this work, a 
      random sub-sample from the ATTICA study's database was studied, consisting of 551 
      men (41 +/- 11 years) and 467 women (38 +/- 11 years), with complete nutritional and 
      biochemical information. Dietary habits were evaluated using a validated 
      food-frequency questionnaire. The dietary antioxidant capacity was based on 
      published values for Italian foods measured by three different assays: 
      ferric-reducing antioxidant power (FRAP), total radical-trapping antioxidant 
      parameter (TRAP) and Trolox equivalent antioxidant capacity (TEAC). Inverse, 
      age-energy adjusted correlations were observed between FRAP and log-glucose (r = 
      -0.149, p = 0.001), log-insulin (r = -0.221, p = 0.001) and log-HOMA-IR (r = 
      -0.186, p = 0.001) concentration, as well as with TRAP and TEAC. After 
      controlling for age, gender, body mass index, physical activity status, smoking 
      habits and energy intake, multi-adjusted analysis confirmed the previous 
      relationships only among participants who were not on the Mediterranean dietary 
      pattern. CONCLUSIONS: Although more prospective studies are required, the data 
      presented support the view that dietary modification towards higher consumption 
      of antioxidants should be implemented in public health strategies, in order to 
      better control glycemic markers in individuals, and prevent the development of 
      diabetes at the population level.
CI  - Copyright (c) 2009 Elsevier B.V. All rights reserved.
FAU - Psaltopoulou, T
AU  - Psaltopoulou T
AD  - Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, 
      University of Athens, Athens, Greece.
FAU - Panagiotakos, D B
AU  - Panagiotakos DB
FAU - Pitsavos, C
AU  - Pitsavos C
FAU - Chrysochoou, C
AU  - Chrysochoou C
FAU - Detopoulou, P
AU  - Detopoulou P
FAU - Skoumas, J
AU  - Skoumas J
FAU - Stefanadis, C
AU  - Stefanadis C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100219
PL  - Netherlands
TA  - Nutr Metab Cardiovasc Dis
JT  - Nutrition, metabolism, and cardiovascular diseases : NMCD
JID - 9111474
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - 0 (Insulin)
SB  - IM
MH  - Adult
MH  - Antioxidants/*administration & dosage
MH  - Biomarkers/*blood
MH  - Body Composition
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus/*blood
MH  - *Diet
MH  - Energy Intake
MH  - Feeding Behavior
MH  - Female
MH  - Glycemic Index
MH  - Greece
MH  - Humans
MH  - Insulin
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Public Health
MH  - Surveys and Questionnaires
EDAT- 2010/02/23 06:00
MHDA- 2011/12/20 06:00
CRDT- 2010/02/23 06:00
PHST- 2009/06/01 00:00 [received]
PHST- 2009/08/08 00:00 [revised]
PHST- 2009/11/17 00:00 [accepted]
PHST- 2010/02/23 06:00 [entrez]
PHST- 2010/02/23 06:00 [pubmed]
PHST- 2011/12/20 06:00 [medline]
AID - S0939-4753(09)00283-X [pii]
AID - 10.1016/j.numecd.2009.11.005 [doi]
PST - ppublish
SO  - Nutr Metab Cardiovasc Dis. 2011 Aug;21(8):561-7. doi: 
      10.1016/j.numecd.2009.11.005. Epub 2010 Feb 19.