PMID- 2018214 OWN - NLM STAT- MEDLINE DCOM- 19910523 LR - 20061115 IS - 0003-2999 (Print) IS - 0003-2999 (Linking) VI - 72 IP - 5 DP - 1991 May TI - Comparison of changes in transit time ultrasound, esophageal Doppler, and thermodilution cardiac output after changes in preload, afterload, and contractility in pigs. PG - 584-8 AB - The purpose of this study was to compare how well changes in cardiac output (CO) measured by esophageal Doppler (Doppler) and thermodilution (TD) followed changes in CO measured by transit time ultrasound (TTU). Simultaneous Doppler, TD, and TTU measurements of CO were made before and after changes in preload, afterload, or contractility in seven piglets. Mean changes in each CO method for each type of change in CO were compared by analysis of variance. Changes in TTU CO, TD CO, and Doppler CO were compared by correlation, linear regression, and bias and precision statistics. Of 86 TTU changes in CO greater than 10%, Doppler changed the same direction as TTU 59 times, changed in an opposite direction 6 times, and changes less than 10% 21 times. Thermodilution changed in the same direction as TTU 72 times, in the opposite direction 4 times, and changed less than 10% 10 times. Changes (% delta) in TTU and TD measurements of CO were not significantly different in any group. Changes in Doppler CO and TTU CO were different for two afterload and contractility groups. Percent changes in Doppler CO had a correlation coefficient (r) = 0.74, m = 0.72, and bias (mean % delta Doppler CO - mean % delta TTU CO) = 6.3 +/- 29.7 with % delta TTU CO. Percent changes in TD CO had an r = 0.90, m = 0.92, and bias = 5.7 +/- 19.1 with % delta TTU CO. Cardiac output measured by Doppler underestimated changes in CO due to changes in preload and contractility and exaggerated changes in CO due to changes in afterload. FAU - Wong, D H AU - Wong DH AD - Department of Anesthesiology, Veterans Administration Medical Center, Long Beach, California 90822. FAU - Watson, T AU - Watson T FAU - Gordon, I AU - Gordon I FAU - Wesley, R AU - Wesley R FAU - Tremper, K K AU - Tremper KK FAU - Zaccari, J AU - Zaccari J FAU - Stemmer, P AU - Stemmer P LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Anesth Analg JT - Anesthesia and analgesia JID - 1310650 SB - IM MH - Analysis of Variance MH - Animals MH - *Cardiac Output MH - Esophagus MH - Myocardial Contraction MH - Swine MH - *Thermodilution MH - Time Factors MH - *Ultrasonics EDAT- 1991/05/01 00:00 MHDA- 1991/05/01 00:01 CRDT- 1991/05/01 00:00 PHST- 1991/05/01 00:00 [pubmed] PHST- 1991/05/01 00:01 [medline] PHST- 1991/05/01 00:00 [entrez] PST - ppublish SO - Anesth Analg. 1991 May;72(5):584-8.