PMID- 20183082
OWN - NLM
STAT- MEDLINE
DCOM- 20100604
LR  - 20171116
IS  - 1532-4109 (Electronic)
IS  - 0360-1234 (Linking)
VI  - 44
IP  - 7
DP  - 2009 Sep
TI  - Determination of veterinary pharmaceuticals in poultry litter and soil by 
      methanol extraction and liquid chromatography-tandem mass spectrometry.
PG  - 717-23
LID - 10.1080/03601230903163863 [doi]
AB  - Pharmaceuticals are emerging contaminants with potential risks to the environment 
      and human health. A liquid chromatography-tandem mass spectrometry (LC-MS-MS) 
      method was developed for determination of the antimicrobials virginiamycin, 
      monensin, salinomycin, narasin and nicarbazin in poultry litter and soil. This 
      method involves methanol extraction and clean-up of extracts through glass 
      microfibre filters, introduction of the extracts and separation of compounds on a 
      Zorbax Eclipse XDB C8 column, and compound detection in a Quattro Micro Micromass 
      spectrometer. For litter samples, Method Detection Limits ranged from 0.1-0.6 
      microg Kg(-1), while Limits of Quantitation (LOQs) were 2, 1, 0.4, 1 and 2 microg 
      Kg(-1) for virginiamycin, monensin, salinomycin, narasin and nicarbazin, 
      respectively. For soil samples calculated LOQs were 2, 3, 1, 1, and 1 microg 
      Kg(-1) for virginiamycin, monensin, salinomycin, narasin and nicarbazin, 
      respectively. Application of the LC-MS-MS method for detection of veterinary 
      pharmaceuticals in litter collected from commercial poultry farms showed that 
      compounds were present at concentrations ranging from 10-11,000 microg Kg(-1).
FAU - Furtula, Vesna
AU  - Furtula V
AD  - Pacific Environmental Science Centre, Environment Canada, North Vancouver, 
      British Columbia, Canada. Vesna.Furtula@ec.gc.ca
FAU - Huang, Lee
AU  - Huang L
FAU - Chambers, Patricia A
AU  - Chambers PA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Environ Sci Health B
JT  - Journal of environmental science and health. Part. B, Pesticides, food 
      contaminants, and agricultural wastes
JID - 7607167
RN  - 0 (Manure)
RN  - 0 (Soil)
RN  - 0 (Veterinary Drugs)
RN  - 0 (fiberglass)
RN  - Y4S76JWI15 (Methanol)
SB  - IM
MH  - Animals
MH  - Chemical Fractionation/*methods
MH  - Chromatography, High Pressure Liquid/methods
MH  - Glass/chemistry
MH  - Humans
MH  - Limit of Detection
MH  - Manure/*analysis
MH  - Methanol/chemistry
MH  - *Poultry
MH  - Soil/*analysis
MH  - Tandem Mass Spectrometry/methods
MH  - Veterinary Drugs/*analysis
EDAT- 2010/02/26 06:00
MHDA- 2010/06/05 06:00
CRDT- 2010/02/26 06:00
PHST- 2010/02/26 06:00 [entrez]
PHST- 2010/02/26 06:00 [pubmed]
PHST- 2010/06/05 06:00 [medline]
AID - 914513014 [pii]
AID - 10.1080/03601230903163863 [doi]
PST - ppublish
SO  - J Environ Sci Health B. 2009 Sep;44(7):717-23. doi: 10.1080/03601230903163863.