PMID- 20186989
OWN - NLM
STAT- MEDLINE
DCOM- 20100722
LR  - 20211020
IS  - 1932-8737 (Electronic)
IS  - 0160-9289 (Print)
IS  - 0160-9289 (Linking)
VI  - 33
IP  - 2
DP  - 2010 Feb
TI  - A left hemiblock improves cardiac resynchronization therapy outcomes in patients 
      with a right bundle branch block.
PG  - 89-93
LID - 10.1002/clc.20708 [doi]
AB  - BACKGROUND: The current recommendation for cardiac resynchronization therapy 
      (CRT) in congestive heart failure (CHF) patients is based on QRS duration, not on 
      QRS morphology. HYPOTHESIS: This study was performed to compare the effects of 
      CRT in CHF patients with pure RBBB vs those with a coexisting left hemiblock 
      (LHB). METHODS AND PATIENT POPULATION: A total of 271 consecutive patients who 
      underwent CRT at Montefiore Medical Center were analyzed. Baseline ECGs were 
      analyzed by 2 reviewers for RBBB and further classified into those with a 
      coexisting LHB. Response to CRT was defined to be, at > or = 6 months after CRT, 
      either an improvement in ejection fraction (EF) of at least 5%, or an improvement 
      in New York Heart Association (NYHA) CHF class. A total of 44 patients were 
      identified: 18 had pure RBBB and 26 had a coexisting LHB. The 2 groups were 
      similar in respect to baseline characteristics (P > 0.05). RESULTS: Only 4 out of 
      18 patients with pure RBBB compared to 18 out of 26 with LHB (P = 0.005) had an 
      improvement in EF > or = 5%. The mean EF was - 1% in the pure RBBB group, but + 
      5.4% in those with LHB (P = 0.0031). Improvement in NYHA class was seen in 0 out 
      of 18 with pure RBBB vs 7 out of 26 patients with LHB (P = 0.03). CONCLUSION: If 
      patients with RBBB also had LHB, their response to CRT was significantly better 
      than if they had RBBB alone.
CI  - Copyright 2010 Wiley Periodicals, Inc.
FAU - Chandra, Ramesh
AU  - Chandra R
AD  - Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York 
      10461, USA.
FAU - Zolty, Ronald
AU  - Zolty R
FAU - Palma, Eugen
AU  - Palma E
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Clin Cardiol
JT  - Clinical cardiology
JID - 7903272
SB  - IM
MH  - Aged
MH  - Bundle-Branch Block/diagnosis/physiopathology/*therapy
MH  - *Cardiac Pacing, Artificial
MH  - Chi-Square Distribution
MH  - Electrocardiography
MH  - Female
MH  - Heart Failure/diagnosis/physiopathology/*therapy
MH  - Humans
MH  - Male
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Function, Left
PMC - PMC6653236
EDAT- 2010/02/27 06:00
MHDA- 2010/07/23 06:00
PMCR- 2010/02/23
CRDT- 2010/02/27 06:00
PHST- 2010/02/27 06:00 [entrez]
PHST- 2010/02/27 06:00 [pubmed]
PHST- 2010/07/23 06:00 [medline]
PHST- 2010/02/23 00:00 [pmc-release]
AID - CLC20708 [pii]
AID - 10.1002/clc.20708 [doi]
PST - ppublish
SO  - Clin Cardiol. 2010 Feb;33(2):89-93. doi: 10.1002/clc.20708.