PMID- 20187877
OWN - NLM
STAT- MEDLINE
DCOM- 20100720
LR  - 20220409
IS  - 1469-8749 (Electronic)
IS  - 0012-1622 (Linking)
VI  - 52
IP  - 7
DP  - 2010 Jul
TI  - The effect of psychosocial stimulation on cognition and behaviour at 6 years in a 
      cohort of term, low-birthweight Jamaican children.
PG  - e148-54
LID - 10.1111/j.1469-8749.2010.03637.x [doi]
AB  - AIM: The aim of this study was to determine whether psychosocial stimulation up 
      to the age of 2 years benefits cognition and behaviour at age 6 years in 
      low-birthweight, term-born (LBW-T) children (gestational age > or =37 wk, 
      birthweight <2500g), and to compare LBW-T and normal-birthweight (NBW) children. 
      METHOD: LBW-T Jamaican infants were randomized at birth to a control group or an 
      intervention group. Children in the intervention group received psychosocial 
      stimulation for 2 years. LBW-T infants were also compared with NBW infants born 
      in the same hospital. IQ, cognitive function, and behaviour were measured at age 
      6 years in 109 LBW-T infants. The LBW-T group were divided into the intervention 
      group (55 out of 70 enrolled, 32 females, 23 males; mean birthweight 2190g, SD 
      200g; and the control group (54 out of 70 enrolled, 33 females, 21 males; 
      birthweight 2240g, SD 180g]. These were compared with 73 out of 94 enrolled NBW 
      infants (38 females 35 males; birthweight 3130g, SD 330g). RESULTS: Among the 
      LBW-T children performance IQ scores were higher in the intervention group than 
      in the control group (regression coefficient [B] 4.06, 95% confidence interval 
      [CI] 0.01-7.98) as were visual-spatial memory scores (B 1.12, 95% CI 0.45-1.87). 
      Children in the intervention group also exhibited fewer behavioural difficulties 
      (B -2.21, 95% CI -4.13 to -0.10) than children in the control group. Compared 
      with NBW children, LBW-T children in the control group had poorer selective 
      attention (B=-3.35, 95% CI -5.59 to -1.26) and visual-spatial memory (B=-0.76, 
      95% CI -1.54 to 0.00), but there were no differences in IQ, language, or 
      behaviour. INTERPRETATION: Stimulation had sustained benefits in LBW-T infants. 
      Finding few differences between LBW-T and NBW school-aged children concurs with 
      results from other developing countries.
FAU - Walker, Susan P
AU  - Walker SP
AD  - Epidemiology Research Unit, Tropical Medicine Research Institute, The University 
      of the West Indies, Mona, Kingston 7, Jamaica. susan.walker@uwimona.edu.jm
FAU - Chang, Susan M
AU  - Chang SM
FAU - Younger, Novie
AU  - Younger N
FAU - Grantham-McGregor, Sally M
AU  - Grantham-McGregor SM
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20100224
PL  - England
TA  - Dev Med Child Neurol
JT  - Developmental medicine and child neurology
JID - 0006761
SB  - IM
CIN - Evid Based Ment Health. 2010 Nov;13(4):128. PMID: 21036990
MH  - Behavior
MH  - Child
MH  - Cognition
MH  - Cognition Disorders/*prevention & control
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - *Infant, Low Birth Weight
MH  - Infant, Newborn
MH  - Intelligence
MH  - Intelligence Tests
MH  - Jamaica
MH  - Male
MH  - Mental Disorders/*prevention & control
MH  - *Mother-Child Relations
MH  - *Play and Playthings
MH  - Psychological Tests
MH  - *Reinforcement, Social
MH  - Treatment Outcome
EDAT- 2010/03/02 06:00
MHDA- 2010/07/21 06:00
CRDT- 2010/03/02 06:00
PHST- 2010/03/02 06:00 [entrez]
PHST- 2010/03/02 06:00 [pubmed]
PHST- 2010/07/21 06:00 [medline]
AID - DMCN3637 [pii]
AID - 10.1111/j.1469-8749.2010.03637.x [doi]
PST - ppublish
SO  - Dev Med Child Neurol. 2010 Jul;52(7):e148-54. doi: 
      10.1111/j.1469-8749.2010.03637.x. Epub 2010 Feb 24.