PMID- 20187929
OWN - NLM
STAT- MEDLINE
DCOM- 20100609
LR  - 20211020
IS  - 1471-2490 (Electronic)
IS  - 1471-2490 (Linking)
VI  - 10
DP  - 2010 Feb 26
TI  - Association between gefitinib and hemorrhagic cystitis and severely contracted 
      bladder: a case report.
PG  - 6
LID - 10.1186/1471-2490-10-6 [doi]
AB  - BACKGROUND: Gefitinib remains an excellent treatment option for patients with a 
      variety of cancers, including non small cell lung cancer (NSCLC). However, 
      clinicians must be aware of the potential of gefitinib to cause an inflammatory 
      reaction in the skin, lungs and bladder. CASE PRESENTATION: We present a case on 
      hemorrhagic cystitis and severely contracted bladder in a patient with NSCLC on 
      gefitinib. CONCLUSIONS: Further studies are needed to substantiate the 
      association of gefitinib therapy with hemorrhagic cystitis and contracted 
      bladder.
FAU - Arakawa, Maki
AU  - Arakawa M
AD  - Department of Urology, Aichi Medical University School of Medicine, Nagakute, 
      Aichi 480-1195, Japan.
FAU - Nakamura, Kogenta
AU  - Nakamura K
FAU - Yamada, Yoshiaki
AU  - Yamada Y
FAU - Rosser, Charles J
AU  - Rosser CJ
FAU - Tobiume, Motoi
AU  - Tobiume M
FAU - Saito, Hiroko
AU  - Saito H
FAU - Hasegawa, Takaaki
AU  - Hasegawa T
FAU - Honda, Nobuaki
AU  - Honda N
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20100226
PL  - England
TA  - BMC Urol
JT  - BMC urology
JID - 100968571
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Quinazolines)
RN  - S65743JHBS (Gefitinib)
SB  - IM
MH  - Antineoplastic Agents/adverse effects/therapeutic use
MH  - Carcinoma, Non-Small-Cell Lung/drug therapy
MH  - Cystitis/*chemically induced/*diagnosis
MH  - Gefitinib
MH  - Hematuria/*chemically induced/*diagnosis
MH  - Humans
MH  - Lung Neoplasms/drug therapy
MH  - Male
MH  - Middle Aged
MH  - Quinazolines/*adverse effects/therapeutic use
MH  - Urinary Bladder Diseases/*chemically induced/*diagnosis
PMC - PMC2839984
EDAT- 2010/03/02 06:00
MHDA- 2010/06/10 06:00
PMCR- 2010/02/26
CRDT- 2010/03/02 06:00
PHST- 2009/06/25 00:00 [received]
PHST- 2010/02/26 00:00 [accepted]
PHST- 2010/03/02 06:00 [entrez]
PHST- 2010/03/02 06:00 [pubmed]
PHST- 2010/06/10 06:00 [medline]
PHST- 2010/02/26 00:00 [pmc-release]
AID - 1471-2490-10-6 [pii]
AID - 10.1186/1471-2490-10-6 [doi]
PST - epublish
SO  - BMC Urol. 2010 Feb 26;10:6. doi: 10.1186/1471-2490-10-6.