PMID- 20188931
OWN - NLM
STAT- MEDLINE
DCOM- 20100520
LR  - 20131121
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 81
IP  - 1-2
DP  - 2010 Apr 15
TI  - Determination of 19 sulfonamides in environmental water samples by automated 
      on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry 
      (SPE-LC-MS/MS).
PG  - 355-66
LID - 10.1016/j.talanta.2009.12.009 [doi]
AB  - The present study describes the development, validation and a practical 
      application of a fully automated analytical method based on on-line solid-phase 
      extraction-liquid chromatography-tandem mass spectrometry (SPE-LC-MS/MS) for the 
      simultaneous determination of 19 sulfonamides, including one acetylated 
      metabolite, in different water matrices. MS/MS detection was carried out in a 
      quadrupole-linear ion trap (QqLIT) mass analyzer. Target compounds were 
      identified in the selected reaction monitoring (SRM) mode, recording two 
      transitions between precursor ions and the two most abundant product ions. The 
      method developed was applied to evaluate the occurrence of the target antibiotics 
      in different water samples: influent and effluent water from waste water 
      treatment plants (WWTP), ground water and surface water. Under optimal 
      conditions, the method detection limits achieved were in the range 0.05-7.84 ng/L 
      for WWTP influent water, 0.01-6.90 ng/L for WWTP effluent water, 0.02-5.13 ng/L 
      for ground water and 0.02-4.52 ng/L for surface water samples. The instrumental 
      repeatability, expressed as RSD, was usually below 10% for the different water 
      matrices. Results showed the wide presence of sulfonamides in the four types of 
      water, including one acetylated metabolite, with maximum concentrations up to 855 
      ng/L corresponding to sulfapyridine in an influent waste water sample near a 
      densely populated urban area.
CI  - (c) 2009 Elsevier B.V. All rights reserved.
FAU - Garcia-Galan, M Jesus
AU  - Garcia-Galan MJ
AD  - Department of Environmental Chemistry, Institute of Environmental Assessment and 
      Water Studies (IDAEA), Spanish Council of Scientific Research (CSIC), Jordi 
      Girona 18-26, E-08034 Barcelona, Spain.
FAU - Diaz-Cruz, M Silvia
AU  - Diaz-Cruz MS
FAU - Barcelo, Damia
AU  - Barcelo D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20091216
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Solvents)
RN  - 0 (Sulfonamides)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Adsorption
MH  - Chromatography, Liquid
MH  - *Environment
MH  - *Online Systems
MH  - Reproducibility of Results
MH  - Rivers/chemistry
MH  - *Solid Phase Extraction
MH  - Solvents/chemistry
MH  - Sulfonamides/*analysis/*isolation & purification/metabolism
MH  - *Tandem Mass Spectrometry
MH  - Waste Disposal, Fluid
MH  - Water/*chemistry
EDAT- 2010/03/02 06:00
MHDA- 2010/05/21 06:00
CRDT- 2010/03/02 06:00
PHST- 2009/07/13 00:00 [received]
PHST- 2009/12/04 00:00 [revised]
PHST- 2009/12/10 00:00 [accepted]
PHST- 2010/03/02 06:00 [entrez]
PHST- 2010/03/02 06:00 [pubmed]
PHST- 2010/05/21 06:00 [medline]
AID - S0039-9140(09)00958-8 [pii]
AID - 10.1016/j.talanta.2009.12.009 [doi]
PST - ppublish
SO  - Talanta. 2010 Apr 15;81(1-2):355-66. doi: 10.1016/j.talanta.2009.12.009. Epub 
      2009 Dec 16.