PMID- 20196820
OWN - NLM
STAT- MEDLINE
DCOM- 20100805
LR  - 20221207
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 75
IP  - 1
DP  - 2010 Jan
TI  - Mapping of susceptibility locus for endometriosis within the HLA region using 
      microsatellite markers in Japanese women.
PG  - 65-7
LID - 10.1111/j.1399-0039.2009.01391.x [doi]
AB  - Endometriosis is a female disorder characterized by the presence of uterine 
      endometrial tissue in ectopic loci. Previous studies reported a higher prevalence 
      of particular human leukocyte antigen (HLA) in endometriosis. In order to confirm 
      the association between endometriosis and the HLA region, 15 polymorphic 
      microsatellite markers distributed in the HLA class II to class III region were 
      subjected to association analysis by polymerase chain reaction (PCR)-based DNA 
      typing of 89 patients and 136 healthy controls. Statistical analysis of the 
      allelic frequency at each microsatellite locus showed that there were no 
      statistically significant differences in the allele frequency distributions 
      between the cases and controls. This finding suggests that the etiology of 
      endometriosis does not involve the HLA class II genomic region and a portion of 
      class III genomic region in the Japanese population.
FAU - Matsuzaka, Y
AU  - Matsuzaka Y
AD  - Department of Molecular Life Science, Tokai University School of Medicine, 
      Bohseidai, Isehara, Kanagawa, Japan.
FAU - Kikuti, Y Y
AU  - Kikuti YY
FAU - Izumi, S
AU  - Izumi S
FAU - Suzuki, T
AU  - Suzuki T
FAU - Cai, L-Y
AU  - Cai LY
FAU - Goya, K
AU  - Goya K
FAU - Inoko, H
AU  - Inoko H
FAU - Makino, T
AU  - Makino T
FAU - Kulski, J K
AU  - Kulski JK
FAU - Kimura, M
AU  - Kimura M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Asian People
MH  - Endometriosis/*genetics
MH  - Female
MH  - Gene Frequency
MH  - *Genes, MHC Class II
MH  - Genetic Association Studies
MH  - *Genetic Predisposition to Disease
MH  - HLA Antigens/*genetics
MH  - Humans
MH  - Microsatellite Repeats
MH  - Middle Aged
MH  - Polymorphism, Genetic
MH  - Uterine Diseases/*genetics
EDAT- 2010/03/04 06:00
MHDA- 2010/08/06 06:00
CRDT- 2010/03/04 06:00
PHST- 2010/03/04 06:00 [entrez]
PHST- 2010/03/04 06:00 [pubmed]
PHST- 2010/08/06 06:00 [medline]
AID - TAN1391 [pii]
AID - 10.1111/j.1399-0039.2009.01391.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2010 Jan;75(1):65-7. doi: 10.1111/j.1399-0039.2009.01391.x.