PMID- 20204419
OWN - NLM
STAT- MEDLINE
DCOM- 20110718
LR  - 20181113
IS  - 1433-7339 (Electronic)
IS  - 0941-4355 (Linking)
VI  - 19
IP  - 4
DP  - 2011 Apr
TI  - Establishing a cancer nutrition rehabilitation program (CNRP) for ambulatory 
      patients attending an Australian cancer center.
PG  - 445-54
LID - 10.1007/s00520-010-0834-9 [doi]
AB  - PURPOSE: To establish a multidisciplinary Cancer Nutrition Rehabilitation Program 
      (CNRP) for the management of the anorexia-cachexia syndrome (ACS) in an 
      Australian cancer center and to evaluate outcomes of 2 months participation in 
      the CNRP METHOD: Patients were eligible if they had significant anorexia/weight 
      loss, identified by their oncologist or the Malnutrition Screening Tool. In the 9 
      months that funding was available, 54 participants (37 males, 17 females; median 
      age, 62 years) enrolled. They had mainly lung or gastrointestinal cancers, with 
      67% receiving chemotherapy concomitantly. Baseline assessments of nutrition and 
      physical status were: median weight 62.7 kg, median weight loss 10.2%, median BMI 
      21.2 kg/m(2), and 78% malnourished according to PG-SGA. Median baseline Karnofsky 
      performance score (KPS) was 70%, with reduced right-hand grip strength (RGHS; 
      median, 27 kg) and endurance (median, 6 min walk test 6MWT 442 m). Patients 
      received individualized nutritional interventions, exercise programs, and symptom 
      management and were followed prospectively for up to 6 months. RESULTS: 
      Twenty-five (58%) of 41 evaluable CNRP participants attended the 2-month 
      follow-up. Median weight (63.4 kg), KPS (80%), endurance (6MWT 570 m), and 
      strength (RGHS 28 kg) were all improved. Edmonton symptom assessment scores (36 
      vs 27) and C-reactive protein levels (39 vs 22) fell. Participants were 
      significantly more likely to return for re-evaluation if at baseline they were 
      having anticancer therapy (odds ratio [OR] 4.7, 95% confidence interval [CI] 
      1.3-16.2) or could walk >420 m in 6 min (OR 21, 95% CI 1.9-227). CONCLUSION: A 
      CNRP may be beneficial for patients with advanced cancer and the ACS, but 
      identification of patients who are likely to stay on the program is needed.
FAU - Glare, Paul
AU  - Glare P
AD  - MSKCC, New York, NY, USA. glarep@mskcc.org
FAU - Jongs, Wendy
AU  - Jongs W
FAU - Zafiropoulos, Bill
AU  - Zafiropoulos B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100305
PL  - Germany
TA  - Support Care Cancer
JT  - Supportive care in cancer : official journal of the Multinational Association of 
      Supportive Care in Cancer
JID - 9302957
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Ambulatory Care/*methods
MH  - Anorexia/etiology/*rehabilitation
MH  - Australia
MH  - C-Reactive Protein/metabolism
MH  - Cachexia/etiology/*rehabilitation
MH  - Cancer Care Facilities
MH  - Female
MH  - Follow-Up Studies
MH  - Hand Strength
MH  - Humans
MH  - Karnofsky Performance Status
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/*complications/therapy
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2010/03/06 06:00
MHDA- 2011/07/19 06:00
CRDT- 2010/03/06 06:00
PHST- 2009/09/23 00:00 [received]
PHST- 2010/02/08 00:00 [accepted]
PHST- 2010/03/06 06:00 [entrez]
PHST- 2010/03/06 06:00 [pubmed]
PHST- 2011/07/19 06:00 [medline]
AID - 10.1007/s00520-010-0834-9 [doi]
PST - ppublish
SO  - Support Care Cancer. 2011 Apr;19(4):445-54. doi: 10.1007/s00520-010-0834-9. Epub 
      2010 Mar 5.