PMID- 20206387 OWN - NLM STAT- MEDLINE DCOM- 20110908 LR - 20181201 IS - 1879-1514 (Electronic) IS - 0166-445X (Linking) VI - 98 IP - 2 DP - 2010 Jun 10 TI - Biomonitoring of perfluorochemicals and toxicity to the downstream fish community of Etobicoke Creek following deployment of aqueous film-forming foam. PG - 120-9 LID - 10.1016/j.aquatox.2010.02.005 [doi] AB - On August 2, 2005, Air France Flight 358 descended on Lester B. Pearson International Airport (Toronto, ON, Canada) during adverse weather conditions and overran the runway, leading to an onboard fire which destroyed the aircraft. Large quantities (48000L) of aqueous film-forming foam (AFFF) were applied to the burning fuselage within meters of Etobicoke Creek. Local authorities could not confirm the identity of the AFFF formulation applied, but chemical analyses of fish livers collected 9 days post-AFFF application indicated that no perfluorinated acids (PFAs) were elevated at the site of application or downstream. This, and higher concentrations of a fluorotelomer sulfonate in fish liver collected downstream, suggests that an AFFF containing telomerized polyfluorinated material was likely used. However, as an urbanized stream within a heavily developed commercial, industrial, and residential watershed, background levels of perfluorinated compounds in Etobicoke Creek were considerable at all sites. Enlarged fish livers adjacent the AFFF-application site, commensurate with depressed peroxisomal beta-oxidation and hepatic oxidative stress, demonstrate some short-term impact of the AFFF on exposed fish within 9 days of its release. Most fish biochemical responses had recovered to normal values by 120 days, although there was some indication that AFFF-associated contamination shifted further downstream over this interval. This study suggests contemporary AFFFs exert relatively low toxicity on fish communities under realistic exposure scenarios. FAU - Oakes, Ken D AU - Oakes KD AD - Dept. of Biology, University of Waterloo, 200 University Ave. W., Waterloo, ON, Canada N2L 3G1. koakes@sciborg.uwaterloo.ca FAU - Benskin, Jonathan P AU - Benskin JP FAU - Martin, Jonathan W AU - Martin JW FAU - Ings, Jennifer S AU - Ings JS FAU - Heinrichs, Jill Y AU - Heinrichs JY FAU - Dixon, D George AU - Dixon DG FAU - Servos, Mark R AU - Servos MR LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100206 PL - Netherlands TA - Aquat Toxicol JT - Aquatic toxicology (Amsterdam, Netherlands) JID - 8500246 RN - 0 (Alkanesulfonic Acids) RN - 0 (Fluorocarbons) RN - 0 (Hydrocarbons, Fluorinated) RN - 0 (Water Pollutants, Chemical) RN - 9H2MAI21CL (perfluorooctane sulfonic acid) SB - IM MH - Aircraft MH - Alkanesulfonic Acids/toxicity MH - Animals MH - Biohazard Release MH - Cities MH - *Environmental Monitoring MH - Fires MH - Fishes/*metabolism MH - Fluorocarbons/toxicity MH - Hydrocarbons, Fluorinated/*toxicity MH - Liver/drug effects/metabolism MH - Ontario MH - Oxidation-Reduction MH - Oxidative Stress/drug effects/physiology MH - Peroxisomes/drug effects/metabolism MH - Rivers/chemistry MH - Time Factors MH - Water Pollutants, Chemical/*toxicity EDAT- 2010/03/09 06:00 MHDA- 2011/09/09 06:00 CRDT- 2010/03/09 06:00 PHST- 2009/11/26 00:00 [received] PHST- 2010/01/22 00:00 [revised] PHST- 2010/02/01 00:00 [accepted] PHST- 2010/03/09 06:00 [entrez] PHST- 2010/03/09 06:00 [pubmed] PHST- 2011/09/09 06:00 [medline] AID - S0166-445X(10)00045-7 [pii] AID - 10.1016/j.aquatox.2010.02.005 [doi] PST - ppublish SO - Aquat Toxicol. 2010 Jun 10;98(2):120-9. doi: 10.1016/j.aquatox.2010.02.005. Epub 2010 Feb 6.