PMID- 20206897
OWN - NLM
STAT- MEDLINE
DCOM- 20100607
LR  - 20101118
IS  - 1532-8414 (Electronic)
IS  - 1071-9164 (Linking)
VI  - 16
IP  - 3
DP  - 2010 Mar
TI  - COPD predicts mortality in HF: the Norwegian Heart Failure Registry.
PG  - 225-9
LID - 10.1016/j.cardfail.2009.12.002 [doi]
AB  - BACKGROUND: Chronic obstructive pulmonary disease (COPD) and chronic heart 
      failure (HF) are common clinical conditions that share tobacco as a risk factor. 
      Our aim was to evaluate the prognostic impact of COPD on HF patients. METHODS AND 
      RESULTS: The Norwegian Heart Failure Registry was used. The study included 4132 
      HF patients (COPD, n = 699) from 22 hospitals (mean follow-up, 13.3 months). COPD 
      patients were older, more often smokers and diabetics, less often on 
      beta-blockers and had a higher heart rate. They were more often in New York Heart 
      Association (NYHA) Class III or IV (COPD, 63%; no COPD, 51%), although left 
      ventricular ejection fraction (LVEF) distribution was similar. COPD independently 
      predicted death (adjusted hazard ratio [HR], 1.188; 95% CI: 1.015 to 1.391; P = 
      0.03) along with age, creatinine, NYHA Class III/IV (HR, 1.464; 95% CI: 1.286 to 
      1.667) and diabetes. beta-blockers at baseline were associated with improved 
      survival in patients with LVEF < or =40% independently of COPD. CONCLUSION: COPD 
      is associated with a poorer survival in HF patients. COPD patients are overrated 
      in terms of NYHA class in comparison with patients with similar LVEF. 
      Nonetheless, NYHA class remains the strongest predictor of death in these 
      patients.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - De Blois, Jonathan
AU  - De Blois J
AD  - Centre Hospitalier Affilie Universitaire de Quebec, Quebec, Canada. 
      jonathan.deblois@med.ulaval.ca
FAU - Simard, Serge
AU  - Simard S
FAU - Atar, Dan
AU  - Atar D
FAU - Agewall, Stefan
AU  - Agewall S
CN  - Norwegian Heart Failure Registry
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20100106
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Analysis of Variance
MH  - *Cause of Death
MH  - Chi-Square Distribution
MH  - Comorbidity
MH  - Female
MH  - Heart Failure/diagnosis/*epidemiology/therapy
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Multivariate Analysis
MH  - Norway
MH  - Predictive Value of Tests
MH  - Probability
MH  - Proportional Hazards Models
MH  - Pulmonary Disease, Chronic Obstructive/diagnosis/*epidemiology/therapy
MH  - Registries
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - Sex Distribution
MH  - Survival Analysis
EDAT- 2010/03/09 06:00
MHDA- 2010/06/09 06:00
CRDT- 2010/03/09 06:00
PHST- 2009/07/23 00:00 [received]
PHST- 2009/11/26 00:00 [revised]
PHST- 2009/12/01 00:00 [accepted]
PHST- 2010/03/09 06:00 [entrez]
PHST- 2010/03/09 06:00 [pubmed]
PHST- 2010/06/09 06:00 [medline]
AID - S1071-9164(09)01195-6 [pii]
AID - 10.1016/j.cardfail.2009.12.002 [doi]
PST - ppublish
SO  - J Card Fail. 2010 Mar;16(3):225-9. doi: 10.1016/j.cardfail.2009.12.002. Epub 2010 
      Jan 6.