PMID- 20223025
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20200930
IS  - 1897-4287 (Electronic)
IS  - 1731-2302 (Print)
IS  - 1731-2302 (Linking)
VI  - 3
IP  - 1
DP  - 2005 Feb 15
TI  - Diagnosis and Management of Multiple Endocrine Neoplasia Type 1 (MEN1).
PG  - 1-6
LID - 10.1186/1897-4287-3-1-1 [doi]
AB  - Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominantly inherited 
      disorder, characterised by the occurrence of tumours of the parathyroid glands, 
      the pancreatic islets, the pituitary gland, the adrenal glands and neuroendocrine 
      carcinoid tumours. Carcinoid tumours of the thymus and pancreatic-duodenal 
      gastrinomas are the most harmful tumour types, since these tumours have malignant 
      potential and curative treatment is difficult to achieve.MEN1 is caused by 
      germline mutations of the MEN1 tumour suppressor gene. Mutation analysis enables 
      mutation carriers to be identified. MEN1 patients and their family members, 
      family members of mutation carriers and patients who are clinically suspected to 
      be carriers of a MEN1 gene mutation are eligible for mutation analysis. 
      MEN1-associated tumours can be detected and treated at an early stage through 
      periodical clinical monitoring of mutation carriers.
FAU - Dreijerink, Koen Ma
AU  - Dreijerink KM
AD  - Department of Endocrinology, University Medical Centre, Utrecht, the Netherlands. 
      c.j.m.lips@azu.nl.
FAU - Lips, Cees Jm
AU  - Lips CJ
LA  - eng
PT  - Journal Article
DEP - 20050215
PL  - Poland
TA  - Hered Cancer Clin Pract
JT  - Hereditary cancer in clinical practice
JID - 101231179
PMC - PMC2837063
EDAT- 2005/01/01 00:00
MHDA- 2005/01/01 00:01
PMCR- 2005/02/15
CRDT- 2010/03/13 06:00
PHST- 2005/01/31 00:00 [received]
PHST- 2005/02/10 00:00 [accepted]
PHST- 2010/03/13 06:00 [entrez]
PHST- 2005/01/01 00:00 [pubmed]
PHST- 2005/01/01 00:01 [medline]
PHST- 2005/02/15 00:00 [pmc-release]
AID - 1897-4287-3-1-1 [pii]
AID - 10.1186/1897-4287-3-1-1 [doi]
PST - epublish
SO  - Hered Cancer Clin Pract. 2005 Feb 15;3(1):1-6. doi: 10.1186/1897-4287-3-1-1.